Ciona intestinalis      Sam68 nuclear body


※ Sam68 nuclear body introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Sam68 nuclear bodies (SNBs) is a kind of these bodies located in Nucleus, Its component of Nucleic acids or RNPs are Chloroplast-specific mRNAs Long non-coding RNA, and it is related to mRNAs trafficking through the nucleus (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID:27838525


There are 6 genes.  Reviewed (0 or Unreviewed (6

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Cii-0180
ENSCING00000014454.2
F6YAV6
2
LLPS-Cii-0547
ENSCING00000007225.3
F6VKZ4
3
LLPS-Cii-1115
ENSCING00000020612.1
H2XX28
4
LLPS-Cii-1564
ENSCING00000002697.3
F6X134
5
LLPS-Cii-1851
ENSCING00000017374.2
F7B1Z2
6
LLPS-Cii-2075
ENSCING00000001244.3
F7AEP7