Cercocebus atys      Sam68 nuclear body


※ Sam68 nuclear body introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Sam68 nuclear bodies (SNBs) is a kind of these bodies located in Nucleus, Its component of Nucleic acids or RNPs are Chloroplast-specific mRNAs Long non-coding RNA, and it is related to mRNAs trafficking through the nucleus (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID:27838525


There are 13 genes.  Reviewed (0 or Unreviewed (13

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Cea-0253
ENSCATG00000034355.1
A0A2K5M8F8
2
LLPS-Cea-2024
ENSCATG00000043560.1
A0A2K5NWS6
3
LLPS-Cea-4124
ENSCATG00000037002.1
A0A2K5MQ51
4
LLPS-Cea-3031
ENSCATG00000039829.1
A0A2K5N8Q0
HNRNPD
5
LLPS-Cea-0098
ENSCATG00000036875.1
A0A2K5MPE9
HNRNPK
6
LLPS-Cea-3377
ENSCATG00000005670.1
A0A2K5KKR7
HNRNPL
7
LLPS-Cea-1667
ENSCATG00000044448.1
A0A2K5P2C6
KHDRBS1
8
LLPS-Cea-2258
ENSCATG00000042976.1
A0A2K5NTK0
KHDRBS2
9
LLPS-Cea-2608
ENSCATG00000034823.1
A0A2K5MB11
KHDRBS3
10
LLPS-Cea-1164
ENSCATG00000030566.1
A0A2K5LIP2
MAK16
11
LLPS-Cea-1863
ENSCATG00000042790.1
A0A2K5NSF8
NGDN
12
LLPS-Cea-2446
ENSCATG00000030326.1
A0A2K5LMT8
TLE3
13
LLPS-Cea-3347
ENSCATG00000036320.1
A0A2K5MKH9
YTHDC1