Canis familiaris      Sam68 nuclear body


※ Sam68 nuclear body introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Sam68 nuclear bodies (SNBs) is a kind of these bodies located in Nucleus, Its component of Nucleic acids or RNPs are Chloroplast-specific mRNAs Long non-coding RNA, and it is related to mRNAs trafficking through the nucleus (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID:27838525


There are 10 genes.  Reviewed (0 or Unreviewed (10

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Caf-2898
ENSCAFG00000006580.4
F1Q3G7
HNRNPA1
2
LLPS-Caf-0607
ENSCAFG00000025045.2
E2RIX2
HNRNPD
3
LLPS-Caf-0132
ENSCAFG00000001399.4
E2RA50
HNRNPK
4
LLPS-Caf-1925
ENSCAFG00000005652.3
E2R944
HNRNPL
5
LLPS-Caf-3234
ENSCAFG00000002470.3
E2QWN2
KHDRBS2
6
LLPS-Caf-1136
ENSCAFG00000006325.4
E2RE19
MAK16
7
LLPS-Caf-0170
ENSCAFG00000011631.3
E2R1X0
NGDN
8
LLPS-Caf-2863
ENSCAFG00000018962.3
E2R068
RBMX
9
LLPS-Caf-0389
ENSCAFG00000007812.3
K9J6P1
SMN
10
LLPS-Caf-1245
ENSCAFG00000002821.4
E2R3C8
YTHDC1