Ailuropoda melanoleuca      Sam68 nuclear body


※ Sam68 nuclear body introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Sam68 nuclear bodies (SNBs) is a kind of these bodies located in Nucleus, Its component of Nucleic acids or RNPs are Chloroplast-specific mRNAs Long non-coding RNA, and it is related to mRNAs trafficking through the nucleus (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID:27838525


There are 10 genes.  Reviewed (0 or Unreviewed (10

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Aim-0369
ENSAMEG00000003316.1
G1L9E2
2
LLPS-Aim-2413
ENSAMEG00000000717.1
G1L1L9
3
LLPS-Aim-3900
ENSAMEG00000008848.1
G1LQL3
4
LLPS-Aim-0489
ENSAMEG00000003926.1
G1LB97
HNRNPK
5
LLPS-Aim-2512
ENSAMEG00000007111.1
G1LKL5
KHDRBS2
6
LLPS-Aim-0355
ENSAMEG00000002852.1
G1L800
MAK16
7
LLPS-Aim-1547
ENSAMEG00000016660.1
G1ME29
NGDN
8
LLPS-Aim-2609
ENSAMEG00000002739.1
D2HD91
RBMXL1
9
LLPS-Aim-2552
ENSAMEG00000015806.1
G1MBP5
TLE3
10
LLPS-Aim-0321
ENSAMEG00000005688.1
G1LGJ3
YTHDC1