※ Receptor cluster introduction

    One of the most actively studied areas in which spatial heterogeneity is emerging as a key factor is signal transduction at the cell membrane. In addition to imposing a quasi-two-dimensional geometry, the membrane plays host to a large diversity of cellular components, and interactions among these components give rise to a complex spatial organization. A central theme of recent work in this field is the prevalence and role of membrane clusters, groups of colocalized molecules that often participate in the detection of external signals and subsequently drive responses within the cell (1).

Reference
1. Mugler A., et al (2012) Membrane Clustering and the Role of Rebinding in Biochemical Signaling. Biophys J, 102(5): 1069–1078. PMID: 22404929

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No.	Status	DrLLPS ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		LLPS-Tag-1113	ENSTGUG00000003555.1	H0YZG0
2		LLPS-Tag-2549	ENSTGUG00000004828.1	H0Z3F5	CFTR
3		LLPS-Tag-1684	ENSTGUG00000000655.1	H0YQX2	ITK
4		LLPS-Tag-0791	ENSTGUG00000012336.1	H0ZQ21	PDE3A
5		LLPS-Tag-2194	ENSTGUG00000006133.1	H0Z6W7	SNAP25
6		LLPS-Tag-0823	ENSTGUG00000000422.1	H0YQ82	SYK