Pongo abelii      Receptor cluster


※ Receptor cluster introduction

    One of the most actively studied areas in which spatial heterogeneity is emerging as a key factor is signal transduction at the cell membrane. In addition to imposing a quasi-two-dimensional geometry, the membrane plays host to a large diversity of cellular components, and interactions among these components give rise to a complex spatial organization. A central theme of recent work in this field is the prevalence and role of membrane clusters, groups of colocalized molecules that often participate in the detection of external signals and subsequently drive responses within the cell (1).

Reference
1. Mugler A., et al (2012) Membrane Clustering and the Role of Rebinding in Biochemical Signaling. Biophys J, 102(5): 1069–1078. PMID: 22404929


There are 8 genes.  Reviewed (0 or Unreviewed (8

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Poa-3118
ENSPPYG00000013910.2
H2PAV4
CAMP
2
LLPS-Poa-4078
ENSPPYG00000017940.2
Q2IBE4
CFTR
3
LLPS-Poa-3133
ENSPPYG00000015986.2
H2PH70
ITK
4
LLPS-Poa-3278
ENSPPYG00000004346.1
H2NGS0
PDE3A
5
LLPS-Poa-0924
ENSPPYG00000007905.2
H2NSI2
SLC2A4
6
LLPS-Poa-1974
ENSPPYG00000010705.2
H2P114
SNAP25
7
LLPS-Poa-3959
ENSPPYG00000017497.2
H2PLX8
STX1A
8
LLPS-Poa-3147
ENSPPYG00000019366.2
H2PSM9
SYK