Pan paniscus      Receptor cluster


※ Receptor cluster introduction

    One of the most actively studied areas in which spatial heterogeneity is emerging as a key factor is signal transduction at the cell membrane. In addition to imposing a quasi-two-dimensional geometry, the membrane plays host to a large diversity of cellular components, and interactions among these components give rise to a complex spatial organization. A central theme of recent work in this field is the prevalence and role of membrane clusters, groups of colocalized molecules that often participate in the detection of external signals and subsequently drive responses within the cell (1).

Reference
1. Mugler A., et al (2012) Membrane Clustering and the Role of Rebinding in Biochemical Signaling. Biophys J, 102(5): 1069–1078. PMID: 22404929


There are 8 genes.  Reviewed (0 or Unreviewed (8

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Pap-1121
ENSPPAG00000042262.1
A0A2R9CDL0
CAMP
2
LLPS-Pap-4016
ENSPPAG00000040492.1
A0A2R9C0G7
CFTR
3
LLPS-Pap-1023
ENSPPAG00000031516.1
A0A2R9AHL5
ITK
4
LLPS-Pap-1028
ENSPPAG00000041912.1
A0A2R9CBQ0
PDE3A
5
LLPS-Pap-0092
ENSPPAG00000003711.1
A0A2R8Z846
SLC2A4
6
LLPS-Pap-4252
ENSPPAG00000028032.1
A0A2R9A2V1
SNAP25
7
LLPS-Pap-3175
ENSPPAG00000043854.1
A0A2R9CKT4
STX1A
8
LLPS-Pap-3790
ENSPPAG00000037645.1
A0A2R9BI29
SYK