Otolemur garnettii      Receptor cluster


※ Receptor cluster introduction

    One of the most actively studied areas in which spatial heterogeneity is emerging as a key factor is signal transduction at the cell membrane. In addition to imposing a quasi-two-dimensional geometry, the membrane plays host to a large diversity of cellular components, and interactions among these components give rise to a complex spatial organization. A central theme of recent work in this field is the prevalence and role of membrane clusters, groups of colocalized molecules that often participate in the detection of external signals and subsequently drive responses within the cell (1).

Reference
1. Mugler A., et al (2012) Membrane Clustering and the Role of Rebinding in Biochemical Signaling. Biophys J, 102(5): 1069–1078. PMID: 22404929


There are 7 genes.  Reviewed (0 or Unreviewed (7

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Otg-4614
ENSOGAG00000002998.2
H0WLW9
CAMP
2
LLPS-Otg-3202
ENSOGAG00000001756.2
H0WJA0
CFTR
3
LLPS-Otg-4700
ENSOGAG00000016539.2
H0XWD5
ITK
4
LLPS-Otg-2579
ENSOGAG00000000846.2
H0WHB6
PDE3A
5
LLPS-Otg-2774
ENSOGAG00000004391.2
H0WPT3
SLC2A4
6
LLPS-Otg-0634
ENSOGAG00000005302.2
H0WRS5
SNAP25
7
LLPS-Otg-2617
ENSOGAG00000011743.2
H0X5F7
SYK