Nomascus leucogenys      Receptor cluster


※ Receptor cluster introduction

    One of the most actively studied areas in which spatial heterogeneity is emerging as a key factor is signal transduction at the cell membrane. In addition to imposing a quasi-two-dimensional geometry, the membrane plays host to a large diversity of cellular components, and interactions among these components give rise to a complex spatial organization. A central theme of recent work in this field is the prevalence and role of membrane clusters, groups of colocalized molecules that often participate in the detection of external signals and subsequently drive responses within the cell (1).

Reference
1. Mugler A., et al (2012) Membrane Clustering and the Role of Rebinding in Biochemical Signaling. Biophys J, 102(5): 1069–1078. PMID: 22404929


There are 7 genes.  Reviewed (0 or Unreviewed (7

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Nol-1643
ENSNLEG00000006404.3
G1R3M3
CAMP
2
LLPS-Nol-4512
ENSNLEG00000011680.2
G1RLX5
CFTR
3
LLPS-Nol-3600
ENSNLEG00000003943.2
G1QV28
ITK
4
LLPS-Nol-4054
ENSNLEG00000004579.2
G1QXA5
PDE3A
5
LLPS-Nol-2276
ENSNLEG00000008058.3
G1R9E2
SLC2A4
6
LLPS-Nol-2389
ENSNLEG00000014426.2
A0A2I3FZK1
SNAP25
7
LLPS-Nol-0340
ENSNLEG00000000438.2
G1QHY9
SYK