Latimeria chalumnae      Receptor cluster


※ Receptor cluster introduction

    One of the most actively studied areas in which spatial heterogeneity is emerging as a key factor is signal transduction at the cell membrane. In addition to imposing a quasi-two-dimensional geometry, the membrane plays host to a large diversity of cellular components, and interactions among these components give rise to a complex spatial organization. A central theme of recent work in this field is the prevalence and role of membrane clusters, groups of colocalized molecules that often participate in the detection of external signals and subsequently drive responses within the cell (1).

Reference
1. Mugler A., et al (2012) Membrane Clustering and the Role of Rebinding in Biochemical Signaling. Biophys J, 102(5): 1069–1078. PMID: 22404929


There are 6 genes.  Reviewed (0 or Unreviewed (6

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Lac-3541
ENSLACG00000002983.1
H3A114
CFTR
2
LLPS-Lac-3081
ENSLACG00000014337.1
H3B303
ITK
3
LLPS-Lac-2051
ENSLACG00000014353.1
H3B321
PDE3A
4
LLPS-Lac-3304
ENSLACG00000014825.1
H3B4L0
SLC2A4
5
LLPS-Lac-1888
ENSLACG00000004234.1
H3A544
SNAP25
6
LLPS-Lac-2552
ENSLACG00000011436.1
H3ATL1
SYK