Ictidomys tridecemlineatus      Receptor cluster


※ Receptor cluster introduction

    One of the most actively studied areas in which spatial heterogeneity is emerging as a key factor is signal transduction at the cell membrane. In addition to imposing a quasi-two-dimensional geometry, the membrane plays host to a large diversity of cellular components, and interactions among these components give rise to a complex spatial organization. A central theme of recent work in this field is the prevalence and role of membrane clusters, groups of colocalized molecules that often participate in the detection of external signals and subsequently drive responses within the cell (1).

Reference
1. Mugler A., et al (2012) Membrane Clustering and the Role of Rebinding in Biochemical Signaling. Biophys J, 102(5): 1069–1078. PMID: 22404929


There are 8 genes.  Reviewed (0 or Unreviewed (8

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Ict-2691
ENSSTOG00000005707.3
I3M6L1
2
LLPS-Ict-4249
ENSSTOG00000015157.3
I3MP90
CAMP
3
LLPS-Ict-3226
ENSSTOG00000009223.3
I3MD63
ITK
4
LLPS-Ict-2487
ENSSTOG00000002257.3
I3M030
PDE3A
5
LLPS-Ict-2873
ENSSTOG00000008616.3
I3MBY4
SLC2A4
6
LLPS-Ict-3466
ENSSTOG00000014169.2
A0A287D0U1
SNAP25
7
LLPS-Ict-3089
ENSSTOG00000009992.3
I3MEM0
STX1A
8
LLPS-Ict-0997
ENSSTOG00000005790.3
I3M6P2
SYK