Manihot esculenta      Perinucleolar compartment


※ Perinucleolar compartment introduction

    The perinucleolar compartment (PNC) is a dynamic, irregularly shaped, and electron-dense nuclear structure that is physically associated with the nucleolus. It is found predominantly in transformed cells and various cancer tissues, and rarely in normal cells (1). The components of the PNC described to date include several small RNAs transcribed by RNA polymerase (pol) III, and several RNA binding proteins of which some are primarily implicated in pre-messenger RNA (mRNA) processing. As a kind of PMLOs, The PNC is a dynamic functional organelle involved in the metabolism and trafficking of a subset of newly synthesized pol III RNAs in transformed cells (2).

Reference
1. Robbins, E., Jentzsch, G., & Micali, A. (1968) The centriole cycle in synchronized HeLa cells. J Cell Biol, 36(2), 329-339. PMID: 5638885
2. Slusarczyk, A., & Huang, S. (2008) The perinucleolar compartment (PNC): detection by immunohistochemistry. Methods Mol Biol, 463, 161-167. PMID: 18951167


There are 1 genes.  Reviewed (0 or Unreviewed (1

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Mae-0984
MANES_05G190000
A0A2C9VXS1
MANES_05G190000