Vitis vinifera      Nuclear speckle


※ Nuclear speckle introduction

    Nuclear speckles or splicing speckles, also known as interchromatin granule clusters, are membrane-less nuclear organelles enriched in pre-mRNA splicing and transcription factors and play important roles in RNA metabolism, such as transcription, pre-mRNA splicing, 3′-end mRNA processing, and execution of mRNA nuclear export (1; 2). They are dynamic subnuclear structures, and their size, shape, and number can vary accompanied with RNA regulation, nuclear speckles disperse in high activity of mRNA processing when transcription or pre-mRNA splicing is inhibited, GSK-3β can regulate assembly of nuclear speckles (2). Because many naturally intronless mRNAs, including eight exogenously expressed and four endogenous ones, are proved to be associate with NSs, So Nuclear speckles (NSs) are thought to serve as splicing factor storage sites (3).

Reference
1. Lee, K. H., Zhang, P., Kim, H. J., Mitrea, D. M., Sarkar, M., Freibaum, B. D., et al. (2016) C9orf72 Dipeptide Repeats Impair the Assembly, Dynamics, and Function of Membrane-Less Organelles. Cell, 167(3), 774-788 e717. PMID: 27768896
2. Wang, K., Wang, L., Wang, J., Chen, S., Shi, M., & Cheng, H. (2018) Intronless mRNAs transit through nuclear speckles to gain export competence. J Cell Biol, 217(11), 3912-3929. PMID: 30194269
3. An, Y., Zou, Y., Cao, Y., Yao, M., Ma, N., Wu, Y., et al. (2019) The nuclear GSK-3beta regulated post-transcriptional processing of mRNA through phosphorylation of SC35. Mol Cell Biochem, 451(1-2), 55-67. PMID: 30030778


There are 55 genes.  Reviewed (0 or Unreviewed (55

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Viv-0157
VIT_12s0059g01420
D7TEE6
COP1
2
LLPS-Viv-1084
VIT_00s0179g00290
F6HBJ1
VIT_00s0179g00290
3
LLPS-Viv-0175
VIT_00s0203g00190
F6I745
VIT_00s0203g00190
4
LLPS-Viv-0725
VIT_00s0264g00120
D7T1S3
VIT_00s0264g00120
5
LLPS-Viv-1465
VIT_01s0011g02040
F6HFR3
VIT_01s0011g02040
6
LLPS-Viv-1719
VIT_01s0150g00590
D7TFN0
VIT_01s0150g00590
7
LLPS-Viv-0196
VIT_02s0025g04000
F6HUE7
VIT_02s0025g04000
8
LLPS-Viv-0313
VIT_03s0017g01220
D7TU93
VIT_03s0017g01220
9
LLPS-Viv-0683
VIT_03s0038g02970
F6I0X3
VIT_03s0038g02970
10
LLPS-Viv-0106
VIT_03s0038g04130
F6I0P5
VIT_03s0038g04130
11
LLPS-Viv-1134
VIT_03s0088g00390
D7T3P2
VIT_03s0088g00390
12
LLPS-Viv-2267
VIT_04s0008g03130
F6H2X4
VIT_04s0008g03130
13
LLPS-Viv-0944
VIT_04s0008g06800
F6H345
VIT_04s0008g06800
14
LLPS-Viv-0938
VIT_04s0008g06810
F6H346
VIT_04s0008g06810
15
LLPS-Viv-0048
VIT_04s0023g01450
F6GWY2
VIT_04s0023g01450
16
LLPS-Viv-0759
VIT_04s0023g01580
F6GWX4
VIT_04s0023g01580
17
LLPS-Viv-0149
VIT_04s0069g00800
D7T0J3
VIT_04s0069g00800
18
LLPS-Viv-0615
VIT_05s0020g01540
D7T6F9
VIT_05s0020g01540
19
LLPS-Viv-0726
VIT_05s0049g01840
D7SZN5
VIT_05s0049g01840
20
LLPS-Viv-2120
VIT_05s0077g02120
F6H6X9
VIT_05s0077g02120
21
LLPS-Viv-0475
VIT_05s0077g02310
D7SYE1
VIT_05s0077g02310
22
LLPS-Viv-0650
VIT_05s0102g00080
D7U1M3
VIT_05s0102g00080
23
LLPS-Viv-0096
VIT_06s0004g00710
F6GUK3
VIT_06s0004g00710
24
LLPS-Viv-1037
VIT_06s0004g04340
D7SKJ4
VIT_06s0004g04340
25
LLPS-Viv-0574
VIT_06s0004g05220
F6GUY6
VIT_06s0004g05220
26
LLPS-Viv-2238
VIT_06s0004g06440
F6GUS5
VIT_06s0004g06440
27
LLPS-Viv-0127
VIT_06s0004g07530
D7SJN7
VIT_06s0004g07530
28
LLPS-Viv-0418
VIT_06s0080g01150
A5ACY7
VIT_06s0080g01150
29
LLPS-Viv-0855
VIT_07s0005g00650
D7U2B0
VIT_07s0005g00650
30
LLPS-Viv-1925
VIT_07s0005g02360
F6HZE7
VIT_07s0005g02360
31
LLPS-Viv-2272
VIT_07s0031g00320
F6H4J2
VIT_07s0031g00320
32
LLPS-Viv-0503
VIT_07s0151g00910
D7TDY1
VIT_07s0151g00910
33
LLPS-Viv-0484
VIT_08s0007g04710
F6HKD0
VIT_08s0007g04710
34
LLPS-Viv-1227
VIT_08s0040g00270
F6HQT0
VIT_08s0040g00270
35
LLPS-Viv-1547
VIT_08s0040g00410
A5AXI5
VIT_08s0040g00410
36
LLPS-Viv-1527
VIT_09s0002g06660
D7U112
VIT_09s0002g06660
37
LLPS-Viv-1485
VIT_09s0002g07070
D7U143
VIT_09s0002g07070
38
LLPS-Viv-2438
VIT_10s0003g04720
F6HLX4
VIT_10s0003g04720
39
LLPS-Viv-2099
VIT_12s0028g01190
E0CTZ3
VIT_12s0028g01190
40
LLPS-Viv-0515
VIT_12s0028g01230
F6H563
VIT_12s0028g01230
41
LLPS-Viv-1337
VIT_12s0142g00110
D7TR31
VIT_12s0142g00110
42
LLPS-Viv-2389
VIT_13s0019g01060
D7TLV0
VIT_13s0019g01060
43
LLPS-Viv-0700
VIT_13s0019g05080
F6HNC0
VIT_13s0019g05080
44
LLPS-Viv-0215
VIT_13s0175g00180
F6I762
VIT_13s0175g00180
45
LLPS-Viv-1140
VIT_14s0006g02280
D7TSY3
VIT_14s0006g02280
46
LLPS-Viv-2298
VIT_14s0030g00480
D7TUZ2
VIT_14s0030g00480
47
LLPS-Viv-0976
VIT_14s0036g00510
F6H620
VIT_14s0036g00510
48
LLPS-Viv-1644
VIT_14s0060g02290
F6I4L9
VIT_14s0060g02290
49
LLPS-Viv-0291
VIT_14s0066g01050
D7TWM5
VIT_14s0066g01050
50
LLPS-Viv-0242
VIT_16s0039g02220
A5BVQ5
VIT_16s0039g02220
51
LLPS-Viv-1364
VIT_16s0098g00320
E0CVI1
VIT_16s0098g00320
52
LLPS-Viv-0732
VIT_17s0000g02840
D7SJ70
VIT_17s0000g02840
53
LLPS-Viv-0069
VIT_17s0000g09500
D7SHG7
VIT_17s0000g09500
54
LLPS-Viv-0735
VIT_18s0001g02200
F6H0J9
VIT_18s0001g02200
55
LLPS-Viv-0647
VIT_19s0014g01440
F6H2P1
VIT_19s0014g01440