Oryza rufipogon      Nuclear speckle


※ Nuclear speckle introduction

    Nuclear speckles or splicing speckles, also known as interchromatin granule clusters, are membrane-less nuclear organelles enriched in pre-mRNA splicing and transcription factors and play important roles in RNA metabolism, such as transcription, pre-mRNA splicing, 3′-end mRNA processing, and execution of mRNA nuclear export (1; 2). They are dynamic subnuclear structures, and their size, shape, and number can vary accompanied with RNA regulation, nuclear speckles disperse in high activity of mRNA processing when transcription or pre-mRNA splicing is inhibited, GSK-3β can regulate assembly of nuclear speckles (2). Because many naturally intronless mRNAs, including eight exogenously expressed and four endogenous ones, are proved to be associate with NSs, So Nuclear speckles (NSs) are thought to serve as splicing factor storage sites (3).

Reference
1. Lee, K. H., Zhang, P., Kim, H. J., Mitrea, D. M., Sarkar, M., Freibaum, B. D., et al. (2016) C9orf72 Dipeptide Repeats Impair the Assembly, Dynamics, and Function of Membrane-Less Organelles. Cell, 167(3), 774-788 e717. PMID: 27768896
2. Wang, K., Wang, L., Wang, J., Chen, S., Shi, M., & Cheng, H. (2018) Intronless mRNAs transit through nuclear speckles to gain export competence. J Cell Biol, 217(11), 3912-3929. PMID: 30194269
3. An, Y., Zou, Y., Cao, Y., Yao, M., Ma, N., Wu, Y., et al. (2019) The nuclear GSK-3beta regulated post-transcriptional processing of mRNA through phosphorylation of SC35. Mol Cell Biochem, 451(1-2), 55-67. PMID: 30030778


There are 56 genes.  Reviewed (0 or Unreviewed (56

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Orr-0195
ORUFI03G11860
A0A0E0NST8
2
LLPS-Orr-0196
ORUFI07G23780
A0A0E0QBG5
3
LLPS-Orr-0223
ORUFI03G32250
A0A0E0P039
4
LLPS-Orr-0228
ORUFI01G09640
A0A0E0MTQ5
5
LLPS-Orr-0299
ORUFI11G22450
A0A0E0RBA9
6
LLPS-Orr-0310
ORUFI03G30920
A0A0E0NZL5
7
LLPS-Orr-0323
ORUFI03G17270
A0A0E0NUT0
8
LLPS-Orr-0422
ORUFI02G00590
A0A0E0N8N2
9
LLPS-Orr-0429
ORUFI07G03180
A0A0E0Q452
10
LLPS-Orr-0443
ORUFI02G35620
A0A0E0NLH5
11
LLPS-Orr-0495
ORUFI04G14770
A0A0E0P9J2
12
LLPS-Orr-0596
ORUFI03G12760
A0A0E0NT72
13
LLPS-Orr-0666
ORUFI06G04460
A0A0E0PU02
14
LLPS-Orr-0687
ORUFI03G43460
A0A0E0P460
15
LLPS-Orr-0758
ORUFI05G16400
A0A0E0PM24
16
LLPS-Orr-0780
ORUFI02G40040
A0A0E0NNB3
17
LLPS-Orr-0819
ORUFI01G47980
A0A0E0N7V2
18
LLPS-Orr-0879
ORUFI03G19730
A0A0E0NVN8
19
LLPS-Orr-0918
ORUFI03G19050
A0A0E0NVF2
20
LLPS-Orr-0999
ORUFI09G17540
A0A0E0QTR0
21
LLPS-Orr-1078
ORUFI02G03690
A0A0E0N9S8
22
LLPS-Orr-1107
ORUFI05G14670
A0A0E0PLF7
23
LLPS-Orr-1177
ORUFI08G07610
A0A0E0QFW2
24
LLPS-Orr-1199
ORUFI10G00670
A0A0E0QVP1
25
LLPS-Orr-1218
ORUFI06G05880
A0A0E0PUG6
26
LLPS-Orr-1276
ORUFI07G04810
A0A0E0Q4S7
27
LLPS-Orr-1330
ORUFI03G13330
A0A0E0NTD9
28
LLPS-Orr-1390
ORUFI03G14720
A0A0E0NTV4
29
LLPS-Orr-1459
ORUFI02G21360
A0A0E0NGA9
30
LLPS-Orr-1465
ORUFI06G01590
A0A0E0PSX0
31
LLPS-Orr-1472
ORUFI12G18300
A0A0E0RJ03
32
LLPS-Orr-1531
ORUFI01G20290
A0A0E0MXE5
33
LLPS-Orr-1579
ORUFI06G11210
A0A0E0PWC1
34
LLPS-Orr-1602
ORUFI09G13660
A0A0E0QSB8
35
LLPS-Orr-1642
ORUFI11G24570
A0A0E0RC17
36
LLPS-Orr-1670
ORUFI01G11320
A0A0E0MUB3
37
LLPS-Orr-1710
ORUFI06G29790
A0A0E0Q2S9
38
LLPS-Orr-1764
ORUFI08G04030
A0A0E0QEM3
39
LLPS-Orr-1779
ORUFI04G09590
A0A0E0P7N3
40
LLPS-Orr-1801
ORUFI02G06210
A0A0E0NAQ9
41
LLPS-Orr-1828
ORUFI04G26440
A0A0E0PDV7
42
LLPS-Orr-1864
ORUFI07G26870
A0A0E0QCL1
43
LLPS-Orr-1898
ORUFI02G34760
A0A0E0NL73
44
LLPS-Orr-1944
ORUFI03G33380
A0A0E0P0H8
45
LLPS-Orr-2055
ORUFI04G11450
A0A0E0P890
46
LLPS-Orr-2066
ORUFI10G13350
A0A0E0R065
47
LLPS-Orr-2086
ORUFI12G12540
A0A0E0RH31
48
LLPS-Orr-2150
ORUFI02G10350
A0A0E0NCB9
49
LLPS-Orr-2163
ORUFI03G17450
A0A0E0NUU9
50
LLPS-Orr-2184
ORUFI03G41250
A0A0E0P3D4
51
LLPS-Orr-2222
ORUFI02G25230
A0A0E0NHN9
52
LLPS-Orr-2308
ORUFI07G02790
A0A0E0Q409
53
LLPS-Orr-2341
ORUFI06G29800
A0A0E0Q2T1
54
LLPS-Orr-2347
ORUFI01G37970
A0A0E0N3X3
55
LLPS-Orr-2348
ORUFI03G13210
A0A0E0NTC2
56
LLPS-Orr-2426
ORUFI02G10080
A0A0E0NC80