Oryza glumaepatula      Nuclear speckle


※ Nuclear speckle introduction

    Nuclear speckles or splicing speckles, also known as interchromatin granule clusters, are membrane-less nuclear organelles enriched in pre-mRNA splicing and transcription factors and play important roles in RNA metabolism, such as transcription, pre-mRNA splicing, 3′-end mRNA processing, and execution of mRNA nuclear export (1; 2). They are dynamic subnuclear structures, and their size, shape, and number can vary accompanied with RNA regulation, nuclear speckles disperse in high activity of mRNA processing when transcription or pre-mRNA splicing is inhibited, GSK-3β can regulate assembly of nuclear speckles (2). Because many naturally intronless mRNAs, including eight exogenously expressed and four endogenous ones, are proved to be associate with NSs, So Nuclear speckles (NSs) are thought to serve as splicing factor storage sites (3).

Reference
1. Lee, K. H., Zhang, P., Kim, H. J., Mitrea, D. M., Sarkar, M., Freibaum, B. D., et al. (2016) C9orf72 Dipeptide Repeats Impair the Assembly, Dynamics, and Function of Membrane-Less Organelles. Cell, 167(3), 774-788 e717. PMID: 27768896
2. Wang, K., Wang, L., Wang, J., Chen, S., Shi, M., & Cheng, H. (2018) Intronless mRNAs transit through nuclear speckles to gain export competence. J Cell Biol, 217(11), 3912-3929. PMID: 30194269
3. An, Y., Zou, Y., Cao, Y., Yao, M., Ma, N., Wu, Y., et al. (2019) The nuclear GSK-3beta regulated post-transcriptional processing of mRNA through phosphorylation of SC35. Mol Cell Biochem, 451(1-2), 55-67. PMID: 30030778


There are 56 genes.  Reviewed (0 or Unreviewed (56

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Orgl-0015
OGLUM03G12720
A0A0D9Z5H4
2
LLPS-Orgl-0024
OGLUM02G33720
A0A0D9YYG0
3
LLPS-Orgl-0025
OGLUM05G07170
A0A0D9ZVL3
4
LLPS-Orgl-0042
OGLUM02G39520
A0A0D9Z0L5
5
LLPS-Orgl-0131
OGLUM03G31240
A0A0D9ZC47
6
LLPS-Orgl-0132
OGLUM03G37390
A0A0D9ZEI6
7
LLPS-Orgl-0146
OGLUM06G11550
A0A0E0A832
8
LLPS-Orgl-0203
OGLUM10G12420
A0A0E0BBG4
9
LLPS-Orgl-0255
OGLUM11G22140
A0A0E0BM77
10
LLPS-Orgl-0266
OGLUM06G29230
A0A0E0AEJ9
11
LLPS-Orgl-0337
OGLUM07G22680
A0A0E0AMW6
12
LLPS-Orgl-0340
OGLUM02G10320
A0A0D9YPT8
13
LLPS-Orgl-0464
OGLUM02G00550
A0A0D9YL49
14
LLPS-Orgl-0471
OGLUM03G17230
A0A0D9Z739
15
LLPS-Orgl-0485
OGLUM03G39350
A0A0D9ZF74
16
LLPS-Orgl-0629
OGLUM11G20030
A0A0E0BLH0
17
LLPS-Orgl-0647
OGLUM02G06050
A0A0D9YN93
18
LLPS-Orgl-0659
OGLUM07G25940
A0A0E0AP47
19
LLPS-Orgl-0742
OGLUM08G03730
A0A0E0AR41
20
LLPS-Orgl-0745
OGLUM04G09970
A0A0D9ZJX8
21
LLPS-Orgl-0838
OGLUM03G17060
A0A0D9Z719
22
LLPS-Orgl-0853
OGLUM10G10550
A0A0E0BAS6
23
LLPS-Orgl-0857
OGLUM01G48850
A0A0D9YKA0
24
LLPS-Orgl-0882
OGLUM04G24690
A0A0D9ZQF7
25
LLPS-Orgl-0906
OGLUM03G19610
A0A0D9Z7Z8
26
LLPS-Orgl-0944
OGLUM06G29190
A0A0E0AEJ3
27
LLPS-Orgl-0946
OGLUM05G16170
A0A0D9ZYR6
28
LLPS-Orgl-1001
OGLUM03G12010
A0A0D9Z580
29
LLPS-Orgl-1006
OGLUM07G02840
A0A0E0AFV8
30
LLPS-Orgl-1008
OGLUM02G20560
A0A0D9YTJ2
31
LLPS-Orgl-1025
OGLUM02G16930
A0A0D9YSB0
32
LLPS-Orgl-1026
OGLUM02G24150
A0A0D9YUU8
33
LLPS-Orgl-1058
OGLUM01G10140
A0A0D9Y5V9
34
LLPS-Orgl-1093
OGLUM07G02360
A0A0E0AFQ4
35
LLPS-Orgl-1109
OGLUM10G00660
A0A0E0B773
36
LLPS-Orgl-1130
OGLUM02G35250
A0A0D9YZ03
37
LLPS-Orgl-1159
OGLUM02G34720
A0A0D9YYT4
38
LLPS-Orgl-1173
OGLUM05G04320
A0A0D9ZUM6
39
LLPS-Orgl-1233
OGLUM03G14200
A0A0D9Z611
40
LLPS-Orgl-1285
OGLUM07G05180
A0A0E0AGP3
41
LLPS-Orgl-1314
OGLUM03G41510
A0A0D9ZG31
42
LLPS-Orgl-1363
OGLUM03G11470
A0A0D9Z513
43
LLPS-Orgl-1381
OGLUM02G36640
A0A0D9YZH2
44
LLPS-Orgl-1385
OGLUM04G08300
A0A0D9ZJ96
45
LLPS-Orgl-1612
OGLUM03G12550
A0A0D9Z5F0
46
LLPS-Orgl-1648
OGLUM01G11880
A0A0D9Y6G2
47
LLPS-Orgl-1662
OGLUM12G18030
A0A0E0BUB6
48
LLPS-Orgl-1713
OGLUM09G16830
A0A0E0B590
49
LLPS-Orgl-1864
OGLUM01G14920
A0A0D9Y7J6
50
LLPS-Orgl-1874
OGLUM09G13110
A0A0E0B3U1
51
LLPS-Orgl-2082
OGLUM07G04530
A0A0E0AGG9
52
LLPS-Orgl-2135
OGLUM06G01600
A0A0E0A4E7
53
LLPS-Orgl-2136
OGLUM12G12830
A0A0E0BSG6
54
LLPS-Orgl-2173
OGLUM01G20870
A0A0D9Y9N5
55
LLPS-Orgl-2318
OGLUM04G13260
A0A0D9ZL41
56
LLPS-Orgl-2344
OGLUM03G18860
A0A0D9Z7Q6