Oryza barthii      Nuclear speckle


※ Nuclear speckle introduction

    Nuclear speckles or splicing speckles, also known as interchromatin granule clusters, are membrane-less nuclear organelles enriched in pre-mRNA splicing and transcription factors and play important roles in RNA metabolism, such as transcription, pre-mRNA splicing, 3′-end mRNA processing, and execution of mRNA nuclear export (1; 2). They are dynamic subnuclear structures, and their size, shape, and number can vary accompanied with RNA regulation, nuclear speckles disperse in high activity of mRNA processing when transcription or pre-mRNA splicing is inhibited, GSK-3β can regulate assembly of nuclear speckles (2). Because many naturally intronless mRNAs, including eight exogenously expressed and four endogenous ones, are proved to be associate with NSs, So Nuclear speckles (NSs) are thought to serve as splicing factor storage sites (3).

Reference
1. Lee, K. H., Zhang, P., Kim, H. J., Mitrea, D. M., Sarkar, M., Freibaum, B. D., et al. (2016) C9orf72 Dipeptide Repeats Impair the Assembly, Dynamics, and Function of Membrane-Less Organelles. Cell, 167(3), 774-788 e717. PMID: 27768896
2. Wang, K., Wang, L., Wang, J., Chen, S., Shi, M., & Cheng, H. (2018) Intronless mRNAs transit through nuclear speckles to gain export competence. J Cell Biol, 217(11), 3912-3929. PMID: 30194269
3. An, Y., Zou, Y., Cao, Y., Yao, M., Ma, N., Wu, Y., et al. (2019) The nuclear GSK-3beta regulated post-transcriptional processing of mRNA through phosphorylation of SC35. Mol Cell Biochem, 451(1-2), 55-67. PMID: 30030778


There are 55 genes.  Reviewed (0 or Unreviewed (55

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Orb-0005
OBART03G18260
A0A0D3FIS2
2
LLPS-Orb-0032
OBART03G31000
A0A0D3FMX7
3
LLPS-Orb-0041
OBART02G00580
A0A0D3EZL4
4
LLPS-Orb-0048
OBART03G12060
A0A0D3FGR1
5
LLPS-Orb-0095
OBART11G20660
A0A0D3HP90
6
LLPS-Orb-0096
OBART02G35370
A0A0D3FBF2
7
LLPS-Orb-0152
OBART03G12660
A0A0D3FGY1
8
LLPS-Orb-0181
OBART02G03660
A0A0D3F0M8
9
LLPS-Orb-0194
OBART03G41660
A0A0D3FRL5
10
LLPS-Orb-0216
OBART03G14050
A0A0D3FHE1
11
LLPS-Orb-0267
OBART04G08350
A0A0D3FUG4
12
LLPS-Orb-0277
OBART10G00670
A0A0D3HAK9
13
LLPS-Orb-0372
OBART06G04500
A0A0D3GD93
14
LLPS-Orb-0423
OBART03G39480
A0A0D3FQV4
15
LLPS-Orb-0460
OBART03G11510
A0A0D3FGJ2
16
LLPS-Orb-0531
OBART06G10610
A0A0D3GF99
17
LLPS-Orb-0659
OBART01G10360
A0A0D3EM32
18
LLPS-Orb-0682
OBART02G38320
A0A0D3FCG0
19
LLPS-Orb-0712
OBART04G10310
A0A0D3FV34
20
LLPS-Orb-0722
OBART02G10360
A0A0D3F305
21
LLPS-Orb-0774
OBART02G34080
A0A0D3FB04
22
LLPS-Orb-0793
OBART05G00430
A0A0D3G2B4
23
LLPS-Orb-0901
OBART01G13220
A0A0D3EN35
24
LLPS-Orb-0920
OBART03G16860
A0A0D3FIB0
25
LLPS-Orb-0924
OBART07G22730
A0A0D3GTR3
26
LLPS-Orb-0978
OBART07G05020
A0A0D3GMX9
27
LLPS-Orb-0988
OBART01G21240
A0A0D3EQQ6
28
LLPS-Orb-1030
OBART03G16670
A0A0D3FI92
29
LLPS-Orb-1058
OBART01G18160
A0A0D3EPN6
30
LLPS-Orb-1193
OBART10G12640
A0A0D3HEH8
31
LLPS-Orb-1219
OBART06G27810
A0A0D3GKZ8
32
LLPS-Orb-1229
OBART03G11680
A0A0D3FGL4
33
LLPS-Orb-1279
OBART08G03610
A0A0D3GWK4
34
LLPS-Orb-1283
OBART03G32000
A0A0D3FNA3
35
LLPS-Orb-1290
OBART07G03480
A0A0D3GME3
36
LLPS-Orb-1313
OBART03G19070
A0A0D3FJ16
37
LLPS-Orb-1351
OBART01G08810
A0A0D3ELK8
38
LLPS-Orb-1389
OBART07G03020
A0A0D3GM97
39
LLPS-Orb-1403
OBART03G12510
A0A0D3FGW3
40
LLPS-Orb-1499
OBART02G23810
A0A0D3F7I5
41
LLPS-Orb-1525
OBART02G06070
A0A0D3F1J7
42
LLPS-Orb-1595
OBART11G22860
A0A0D3HPZ1
43
LLPS-Orb-1615
OBART05G15300
A0A0D3G794
44
LLPS-Orb-1672
OBART02G23700
A0A0D3F7H3
45
LLPS-Orb-1698
OBART05G06820
A0A0D3G4D7
46
LLPS-Orb-1740
OBART01G19120
A0A0D3EQ05
47
LLPS-Orb-1752
OBART06G01600
A0A0D3GC94
48
LLPS-Orb-1838
OBART03G29710
A0A0D3FMG9
49
LLPS-Orb-1925
OBART12G16470
A0A0D3HVX7
50
LLPS-Orb-1963
OBART07G25930
A0A0D3GUU3
51
LLPS-Orb-1972
OBART02G33210
A0A0D3FAQ5
52
LLPS-Orb-2036
OBART06G28190
A0A0D3GL39
53
LLPS-Orb-2085
OBART04G13560
A0A0D3FW66
54
LLPS-Orb-2264
OBART01G34610
A0A0D3EVA9
55
LLPS-Orb-2331
OBART09G16220
A0A0D3H8V0