Tetraodon nigroviridis      Neuronal granule


※ Neuronal granule introduction

    Neuronal granules are also referred to as neuronal transport granules, RNA-transporting granules, neuronal RNA granules, dendritic P-body like structures (dlP-bodies), FMRP granules and Staufen granules(1,2). They are broadly identified by the presence of two highly conserved proteins: Staufen, a double-stranded RNA-binding protein and FMRP. As a kind of cytoplasmic RNP bodies located in Cytoplasm of neurons, neuronal transport RNPs have highly specialized functions and have been shown to interact or co-localize with components of GW/P bodies (1), it's microtubule-dependent and contain Silenced mRNAs and ribosomes components. Neuronal RNA bodies is of spherical shape with fluid characteristics, proved to be associated with rotein synthesis in response to exogenous stimuli (2).

Reference
1. Moser, J. J., & Fritzler, M. J. (2013) Relationship of other cytoplasmic ribonucleoprotein bodies (cRNPB) to GW/P bodies. Adv Exp Med Biol, 768, 213-242. PMID: 23224973
2. Hirano, M., Muto, M., Sakai, M., Kondo, H., Kobayashi, S., Kariwa, H., Yoshii, K.(2017) Dendritic transport of tick-borne flavivirus RNA by neuronal granules affects development of neurological disease. Proc Natl Acad Sci U S A, 114, 9960–9965. PMID: 28847946
3. Darling, A. L., Liu, Y., Oldfield, C. J., & Uversky, V. N. (2018) Intrinsically Disordered Proteome of Human Membrane-Less Organelles. Proteomics, 18(5-6), e1700193. PMID: 27838525


There are 33 genes.  Reviewed (0 or Unreviewed (33

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Ten-0000
ENSTNIG00000014732.1
H3DB76
2
LLPS-Ten-0035
ENSTNIG00000016309.1
H3DFV9
3
LLPS-Ten-0103
ENSTNIG00000003790.1
H3CDR7
4
LLPS-Ten-0136
ENSTNIG00000012013.1
H3D386
5
LLPS-Ten-0597
ENSTNIG00000011331.1
H3D188
6
LLPS-Ten-0614
ENSTNIG00000005118.1
H3CHQ8
7
LLPS-Ten-0822
ENSTNIG00000009725.1
H3C8R3
8
LLPS-Ten-0885
ENSTNIG00000010005.1
H3CXB5
9
LLPS-Ten-0970
ENSTNIG00000012954.1
H3D5Z3
10
LLPS-Ten-1249
ENSTNIG00000013499.1
H3D7K3
11
LLPS-Ten-1397
ENSTNIG00000016043.1
H3DF38
12
LLPS-Ten-1435
ENSTNIG00000008582.1
H3CT38
13
LLPS-Ten-1486
ENSTNIG00000013071.1
H3D6B2
14
LLPS-Ten-1507
ENSTNIG00000007398.1
H3CPM1
15
LLPS-Ten-1509
ENSTNIG00000010358.1
H3CYC9
16
LLPS-Ten-1639
ENSTNIG00000012186.1
H3D3R2
17
LLPS-Ten-2047
ENSTNIG00000011202.1
H3D0V1
18
LLPS-Ten-2344
ENSTNIG00000015485.1
H3DDG2
19
LLPS-Ten-2404
ENSTNIG00000007110.1
H3CNS8
20
LLPS-Ten-2460
ENSTNIG00000011266.1
H3D119
21
LLPS-Ten-2719
ENSTNIG00000017299.1
H3DIU3
22
LLPS-Ten-2915
ENSTNIG00000009935.1
H3CX42
23
LLPS-Ten-3308
ENSTNIG00000015078.1
H3DC89
24
LLPS-Ten-3314
ENSTNIG00000008181.1
H3CRX3
25
LLPS-Ten-3342
ENSTNIG00000002618.1
H3CA99
26
LLPS-Ten-a053
ENSTNIG00000011848.1
H3D2R5
27
LLPS-Ten-2150
ENSTNIG00000018221.1
H3DLI9
CPEB4
28
LLPS-Ten-2371
ENSTNIG00000017510.1
H3DJF8
DDX5
29
LLPS-Ten-0600
ENSTNIG00000005642.1
Q4SYL0
GSTENG00010276001
30
LLPS-Ten-2323
ENSTNIG00000007596.1
Q4SQ34
GSTENG00014543001
31
LLPS-Ten-1333
ENSTNIG00000010342.1
Q4SEE5
GSTENG00019594001
32
LLPS-Ten-1033
ENSTNIG00000012223.1
Q4S739
GSTENG00022999001
33
LLPS-Ten-2408
ENSTNIG00000002484.1
H3C9W2
RTCB