Sus scrofa      Neuronal granule


※ Neuronal granule introduction

    Neuronal granules are also referred to as neuronal transport granules, RNA-transporting granules, neuronal RNA granules, dendritic P-body like structures (dlP-bodies), FMRP granules and Staufen granules(1,2). They are broadly identified by the presence of two highly conserved proteins: Staufen, a double-stranded RNA-binding protein and FMRP. As a kind of cytoplasmic RNP bodies located in Cytoplasm of neurons, neuronal transport RNPs have highly specialized functions and have been shown to interact or co-localize with components of GW/P bodies (1), it's microtubule-dependent and contain Silenced mRNAs and ribosomes components. Neuronal RNA bodies is of spherical shape with fluid characteristics, proved to be associated with rotein synthesis in response to exogenous stimuli (2).

Reference
1. Moser, J. J., & Fritzler, M. J. (2013) Relationship of other cytoplasmic ribonucleoprotein bodies (cRNPB) to GW/P bodies. Adv Exp Med Biol, 768, 213-242. PMID: 23224973
2. Hirano, M., Muto, M., Sakai, M., Kondo, H., Kobayashi, S., Kariwa, H., Yoshii, K.(2017) Dendritic transport of tick-borne flavivirus RNA by neuronal granules affects development of neurological disease. Proc Natl Acad Sci U S A, 114, 9960–9965. PMID: 28847946
3. Darling, A. L., Liu, Y., Oldfield, C. J., & Uversky, V. N. (2018) Intrinsically Disordered Proteome of Human Membrane-Less Organelles. Proteomics, 18(5-6), e1700193. PMID: 27838525


There are 43 genes.  Reviewed (0 or Unreviewed (43

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Sus-0377
ENSSSCG00000032655.1
A0A287BET5
ALYREF
2
LLPS-Sus-1783
ENSSSCG00000013305.3
F1SGS6
CAPRIN1
3
LLPS-Sus-3389
ENSSSCG00000013427.3
A0A286ZNG8
CIRBP
4
LLPS-Sus-1423
ENSSSCG00000016981.3
A0A287A8S6
CPEB4
5
LLPS-Sus-1207
ENSSSCG00000008619.3
F1SCS1
DDX1
6
LLPS-Sus-0243
ENSSSCG00000012252.3
F1RX16
DDX3X
7
LLPS-Sus-0455
ENSSSCG00000032092.1
A0A287ACV3
DDX5
8
LLPS-Sus-1503
ENSSSCG00000004489.3
A0A287AJQ9
EEF1A1
9
LLPS-Sus-1732
ENSSSCG00000011710.3
A0A287AUH4
EIF2A
10
LLPS-Sus-2275
ENSSSCG00000033295.1
A0A287A096
EIF2S1
11
LLPS-Sus-0789
ENSSSCG00000026617.2
F1S4Y8
EIF2S2
12
LLPS-Sus-0111
ENSSSCG00000028420.2
F1S0B9
EIF4E
13
LLPS-Sus-2183
ENSSSCG00000037291.1
A0A287BJS6
ELAVL4
14
LLPS-Sus-3401
ENSSSCG00000009974.3
A0A287APW0
EWSR1
15
LLPS-Sus-2044
ENSSSCG00000012727.4
K7GSF4
FMR1
16
LLPS-Sus-1600
ENSSSCG00000011769.3
I3LH62
FXR1
17
LLPS-Sus-2477
ENSSSCG00000017953.4
F1ST39
FXR2
18
LLPS-Sus-1972
ENSSSCG00000035676.1
A0A286ZTN5
G3BP1
19
LLPS-Sus-3475
ENSSSCG00000000288.3
A0A286ZPE3
HNRNPA1
20
LLPS-Sus-2441
ENSSSCG00000036350.1
A0A286ZI52
HNRNPA2B1
21
LLPS-Sus-1821
ENSSSCG00000014031.3
A0A287BMB6
HNRNPAB
22
LLPS-Sus-0964
ENSSSCG00000009249.3
F1RVC9
HNRNPD
23
LLPS-Sus-3489
ENSSSCG00000010877.3
A0A286ZVL0
HNRNPU
24
LLPS-Sus-0446
ENSSSCG00000023122.2
I3LP11
KHDRBS1
25
LLPS-Sus-3897
ENSSSCG00000010380.4
K7GRS5
MAPK8
26
LLPS-Sus-2169
ENSSSCG00000016275.3
F1SMV6
NCL
27
LLPS-Sus-0568
ENSSSCG00000023245.2
I3LSU1
NONO
28
LLPS-Sus-a065
ENSSSCG00000010581.3
F1S860
PSD
29
LLPS-Sus-0940
ENSSSCG00000009569.3
A0A286ZKW2
PSPC1
30
LLPS-Sus-0740
ENSSSCG00000021591.2
I3L5X7
RBM3
31
LLPS-Sus-1388
ENSSSCG00000015846.3
A0A287BLU9
RBPMS
32
LLPS-Sus-3100
ENSSSCG00000012083.3
F1SG49
RIPK4
33
LLPS-Sus-1520
ENSSSCG00000040494.1
A0A287B5V1
RPL3
34
LLPS-Sus-1112
ENSSSCG00000000158.3
F2Z5V0
RTCB
35
LLPS-Sus-1672
ENSSSCG00000005029.3
A0A287B7A0
RTRAF
36
LLPS-Sus-0045
ENSSSCG00000035690.1
A0A287A4F2
SFPQ
37
LLPS-Sus-2078
ENSSSCG00000036293.1
A0A287B770
SRSF10
38
LLPS-Sus-0357
ENSSSCG00000027444.2
A0A286ZQP6
STAU1
39
LLPS-Sus-0195
ENSSSCG00000006179.3
A0A287A6A7
STAU2
40
LLPS-Sus-0705
ENSSSCG00000004294.3
F2Z5D4
SYNCRIP
41
LLPS-Sus-4742
ENSSSCG00000029200.2
F1RX21
TRIM2
42
LLPS-Sus-4187
ENSSSCG00000014625.3
F1RMN8
TRIM3
43
LLPS-Sus-4548
ENSSSCG00000000292.3
A0A287ARD9
ZNF385A