Scophthalmus maximus      Neuronal granule


※ Neuronal granule introduction

    Neuronal granules are also referred to as neuronal transport granules, RNA-transporting granules, neuronal RNA granules, dendritic P-body like structures (dlP-bodies), FMRP granules and Staufen granules(1,2). They are broadly identified by the presence of two highly conserved proteins: Staufen, a double-stranded RNA-binding protein and FMRP. As a kind of cytoplasmic RNP bodies located in Cytoplasm of neurons, neuronal transport RNPs have highly specialized functions and have been shown to interact or co-localize with components of GW/P bodies (1), it's microtubule-dependent and contain Silenced mRNAs and ribosomes components. Neuronal RNA bodies is of spherical shape with fluid characteristics, proved to be associated with rotein synthesis in response to exogenous stimuli (2).

Reference
1. Moser, J. J., & Fritzler, M. J. (2013) Relationship of other cytoplasmic ribonucleoprotein bodies (cRNPB) to GW/P bodies. Adv Exp Med Biol, 768, 213-242. PMID: 23224973
2. Hirano, M., Muto, M., Sakai, M., Kondo, H., Kobayashi, S., Kariwa, H., Yoshii, K.(2017) Dendritic transport of tick-borne flavivirus RNA by neuronal granules affects development of neurological disease. Proc Natl Acad Sci U S A, 114, 9960–9965. PMID: 28847946
3. Darling, A. L., Liu, Y., Oldfield, C. J., & Uversky, V. N. (2018) Intrinsically Disordered Proteome of Human Membrane-Less Organelles. Proteomics, 18(5-6), e1700193. PMID: 27838525


There are 34 genes.  Reviewed (0 or Unreviewed (34

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Scm-0235
ENSSMAG00000004730.1
2
LLPS-Scm-0417
ENSSMAG00000003760.1
3
LLPS-Scm-1712
ENSSMAG00000010279.1
4
LLPS-Scm-2863
ENSSMAG00000005096.1
A0A2U9BPL2
RTCB
5
LLPS-Scm-0452
ENSSMAG00000002566.1
A0A2U9CVX3
SMAX5B_000200
6
LLPS-Scm-2169
ENSSMAG00000020337.1
A0A2U9CIM0
SMAX5B_000475
7
LLPS-Scm-0290
ENSSMAG00000010349.1
A0A2U9BRS9
SMAX5B_001555
8
LLPS-Scm-0581
ENSSMAG00000016487.1
A0A2U9CVU4
SMAX5B_001825
9
LLPS-Scm-1935
ENSSMAG00000017410.1
A0A2U9BFW4
SMAX5B_002333
10
LLPS-Scm-2205
ENSSMAG00000003165.1
A0A2U9AWZ6
SMAX5B_002538
11
LLPS-Scm-1008
ENSSMAG00000014875.1
A0A2U9BYQ4
SMAX5B_003257
12
LLPS-Scm-1348
ENSSMAG00000001761.1
A0A2U9AVH3
SMAX5B_003928
13
LLPS-Scm-2836
ENSSMAG00000011590.1
A0A2U9B812
SMAX5B_004318
14
LLPS-Scm-2578
ENSSMAG00000001147.1
A0A2U9B955
SMAX5B_004819
15
LLPS-Scm-1089
ENSSMAG00000007582.1
A0A2U9BL14
SMAX5B_005873
16
LLPS-Scm-0686
ENSSMAG00000001696.1
A0A2U9B7C8
SMAX5B_006785
17
LLPS-Scm-0001
ENSSMAG00000017903.1
A0A2U9BP27
SMAX5B_007543
18
LLPS-Scm-1093
ENSSMAG00000010094.1
A0A2U9CTH4
SMAX5B_008123
19
LLPS-Scm-0643
ENSSMAG00000003607.1
A0A2U9CVM1
SMAX5B_008345
20
LLPS-Scm-1614
ENSSMAG00000010570.1
A0A2U9BWK9
SMAX5B_010127
21
LLPS-Scm-2810
ENSSMAG00000002205.1
A0A2U9BNI9
SMAX5B_011562
22
LLPS-Scm-3475
ENSSMAG00000002579.1
A0A2U9AVE9
SMAX5B_015266
23
LLPS-Scm-1848
ENSSMAG00000018201.1
A0A2U9CZ25
SMAX5B_015910
24
LLPS-Scm-0916
ENSSMAG00000014028.1
A0A2U9CUY5
SMAX5B_016075
25
LLPS-Scm-2960
ENSSMAG00000020593.1
A0A2U9BMG5
SMAX5B_016295
26
LLPS-Scm-0186
ENSSMAG00000006669.1
A0A2U9C6B5
SMAX5B_016461
27
LLPS-Scm-0808
ENSSMAG00000009686.1
A0A2U9B9Z9
SMAX5B_016995
28
LLPS-Scm-3399
ENSSMAG00000005233.1
A0A2U9B6K2
SMAX5B_017163
29
LLPS-Scm-0115
ENSSMAG00000010015.1
A0A2U9C5A4
SMAX5B_018995
30
LLPS-Scm-0421
ENSSMAG00000013698.1
A0A2U9C7F4
SMAX5B_018999
31
LLPS-Scm-1552
ENSSMAG00000010871.1
A0A2U9B153
SMAX5B_019490
32
LLPS-Scm-1288
ENSSMAG00000003896.1
A0A2U9B452
SMAX5B_019959
33
LLPS-Scm-0980
ENSSMAG00000019240.1
A0A2U9C4C2
SMAX5B_020479
34
LLPS-Scm-1394
ENSSMAG00000006881.1
A0A2U9C4I4
SMAX5B_022221