Tursiops truncatus      Mitochondrial RNA granule


※ Mitochondrial RNA granule introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Mitochondrial RNA granules is a kind of these bodies of spherical shape that located in mitochondria with mitochondrial mRNAs and mitochondrial ribosomes components and it’s proved to be related to the posttranscriptional RNA processing and biogenesis of mitochondrial ribosomes (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID: 27838525


There are 23 genes.  Reviewed (0 or Unreviewed (23

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Tut-0841
ENSTTRG00000002314.1
A0A2U3V1Q8
DHX30
2
LLPS-Tut-2367
ENSTTRG00000004107.1
A0A2U4AP29
ERAL1
3
LLPS-Tut-2215
ENSTTRG00000000853.1
A0A2U4AYA0
FASTK
4
LLPS-Tut-0771
ENSTTRG00000009846.1
A0A2U3V6I7
FASTKD2
5
LLPS-Tut-0053
ENSTTRG00000011450.1
A0A2U3V9C5
HSD17B10
6
LLPS-Tut-2231
ENSTTRG00000007967.1
A0A2U4AF34
KIAA0391
7
LLPS-Tut-1911
ENSTTRG00000003006.1
A0A2U4AZ09
LOC101320538
8
LLPS-Tut-0727
ENSTTRG00000006938.1
A0A2U4BWQ0
LOC101323867
9
LLPS-Tut-1045
ENSTTRG00000010687.1
A0A2U4AHI7
MRM2
10
LLPS-Tut-0602
ENSTTRG00000003844.1
A0A2U4ANG3
MRM3
11
LLPS-Tut-0230
ENSTTRG00000014082.1
A0A2U3V5D5
MRPL19
12
LLPS-Tut-1282
ENSTTRG00000015111.1
A0A2U4BQM4
MRPL43
13
LLPS-Tut-1163
ENSTTRG00000011837.1
A0A2U4AWU9
MRPS27
14
LLPS-Tut-0196
ENSTTRG00000012556.1
A0A2U4BGD5
MRPS31
15
LLPS-Tut-1557
ENSTTRG00000014421.1
A0A2U3V0V2
MRPS7
16
LLPS-Tut-1824
ENSTTRG00000007349.1
A0A2U4AI49
MTERF3
17
LLPS-Tut-1432
ENSTTRG00000010699.1
A0A2U4BSN0
PMPCB
18
LLPS-Tut-1125
ENSTTRG00000000029.1
A0A2U4BY37
PNPT1
19
LLPS-Tut-1005
ENSTTRG00000011851.1
A0A2U4AWT2
PTCD2
20
LLPS-Tut-2393
ENSTTRG00000007544.1
A0A2U4C415
RPUSD3
21
LLPS-Tut-1680
ENSTTRG00000001555.1
A0A2U3V6Q0
RPUSD4
22
LLPS-Tut-0667
ENSTTRG00000006327.1
A0A2U4CNZ4
TFB1M
23
LLPS-Tut-2506
ENSTTRG00000015004.1
A0A2U3V6F3
TRMT10C