※ Mitochondrial RNA granule introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Mitochondrial RNA granules is a kind of these bodies of spherical shape that located in mitochondria with mitochondrial mRNAs and mitochondrial ribosomes components and it’s proved to be related to the posttranscriptional RNA processing and biogenesis of mitochondrial ribosomes (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID: 27838525

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No.	Status	DrLLPS ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		LLPS-Sus-0710	ENSSSCG00000001706.3	A0A287B287	AARS2
2		LLPS-Sus-0213	ENSSSCG00000015492.3	F1S742	DARS2
3		LLPS-Sus-3403	ENSSSCG00000026038.2	I3LB32	DDX28
4		LLPS-Sus-3596	ENSSSCG00000011342.3	A0A287AET0	DHX30
5		LLPS-Sus-4151	ENSSSCG00000017776.3	F1RNA7	ERAL1
6		LLPS-Sus-3250	ENSSSCG00000024184.2	I3LGI3	FASTK
7		LLPS-Sus-2225	ENSSSCG00000015933.3	A0A287B180	FASTKD1
8		LLPS-Sus-2774	ENSSSCG00000016134.3	F1SHC9	FASTKD2
9		LLPS-Sus-3497	ENSSSCG00000008940.3	F1RUP2	GRSF1
10		LLPS-Sus-1576	ENSSSCG00000012327.4	K7GP28	HSD17B10
11		LLPS-Sus-0560	ENSSSCG00000001950.3	A0A287AVI5	KIAA0391
12		LLPS-Sus-0720	ENSSSCG00000010290.3	F1SU78	MCU
13		LLPS-Sus-1605	ENSSSCG00000004522.3	F1RPN9	ME2
14		LLPS-Sus-3624	ENSSSCG00000017691.3	F1S1B8	MRM1
15		LLPS-Sus-2787	ENSSSCG00000036247.1	A0A287A464	MRM2
16		LLPS-Sus-3534	ENSSSCG00000017806.3	F1RHK0	MRM3
17		LLPS-Sus-2589	ENSSSCG00000021007.2	I3LNJ0	MRPL19
18		LLPS-Sus-4523	ENSSSCG00000010560.3	F1S8U4	MRPL43
19		LLPS-Sus-2333	ENSSSCG00000011763.3	F1SGC7	MRPL47
20		LLPS-Sus-2491	ENSSSCG00000023818.2	I3LK09	MRPS27
21		LLPS-Sus-2829	ENSSSCG00000009372.3	A0A287AR81	MRPS31
22		LLPS-Sus-0248	ENSSSCG00000035134.1	A0A286ZJ25	MRPS7
23		LLPS-Sus-2256	ENSSSCG00000028020.2	I3LU08	MRPS9
24		LLPS-Sus-1142	ENSSSCG00000006090.3	F1RY61	MTERF3
25		LLPS-Sus-4363	ENSSSCG00000011018.3	F1RWE3	MTPAP
26		LLPS-Sus-4194	ENSSSCG00000015113.3	F1SAH1	NLRX1
27		LLPS-Sus-3700	ENSSSCG00000025792.2	I3LQI1	NOA1
28		LLPS-Sus-1916	ENSSSCG00000015422.3	F1SB55	PMPCB
29		LLPS-Sus-2917	ENSSSCG00000031882.1	A0A287AMV5	PNPT1
30		LLPS-Sus-0925	ENSSSCG00000035693.1	A0A287BLR6	POLRMT
31		LLPS-Sus-1954	ENSSSCG00000007622.3	F1RNS9	PTCD1
32		LLPS-Sus-4291	ENSSSCG00000016975.3	F1SK11	PTCD2
33		LLPS-Sus-3535	ENSSSCG00000011555.3	F1SQE3	RPUSD3
34		LLPS-Sus-3947	ENSSSCG00000015233.3	F1S6H1	RPUSD4
35		LLPS-Sus-2016	ENSSSCG00000011501.3	A0A286ZWJ9	SUCLG2
36		LLPS-Sus-2128	ENSSSCG00000010251.3	F1SUG1	SUPV3L1
37		LLPS-Sus-4800	ENSSSCG00000024361.2	I3LVN4	TFB1M
38		LLPS-Sus-4173	ENSSSCG00000011956.2	F1SL15	TRMT10C
39		LLPS-Sus-0334	ENSSSCG00000005645.3	A0A287B3P1	TRUB2
40		LLPS-Sus-3509	ENSSSCG00000030428.2	I3LNP8	TWNK
41		LLPS-Sus-1650	ENSSSCG00000011066.3	A0A287A9J1	YME1L1