Schizosaccharomyces cryophilus      Mitochondrial RNA granule


※ Mitochondrial RNA granule introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Mitochondrial RNA granules is a kind of these bodies of spherical shape that located in mitochondria with mitochondrial mRNAs and mitochondrial ribosomes components and it’s proved to be related to the posttranscriptional RNA processing and biogenesis of mitochondrial ribosomes (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID: 27838525


There are 10 genes.  Reviewed (0 or Unreviewed (10

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Scc-0653
SPOG_00986
S9VVR1
SPOG_00986
2
LLPS-Scc-0694
SPOG_01247
S9X9P9
SPOG_01247
3
LLPS-Scc-0774
SPOG_01655
S9W1X0
SPOG_01655
4
LLPS-Scc-1156
SPOG_02070
S9W438
SPOG_02070
5
LLPS-Scc-0903
SPOG_02354
S9X241
SPOG_02354
6
LLPS-Scc-0618
SPOG_02598
S9X2W4
SPOG_02598
7
LLPS-Scc-0447
SPOG_03430
S9X866
SPOG_03430
8
LLPS-Scc-0561
SPOG_03487
S9VPY2
SPOG_03487
9
LLPS-Scc-1078
SPOG_04482
S9W0X2
SPOG_04482
10
LLPS-Scc-1396
SPOG_04849
S9X529
SPOG_04849