Sarcophilus harrisii      Mitochondrial RNA granule


※ Mitochondrial RNA granule introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Mitochondrial RNA granules is a kind of these bodies of spherical shape that located in mitochondria with mitochondrial mRNAs and mitochondrial ribosomes components and it’s proved to be related to the posttranscriptional RNA processing and biogenesis of mitochondrial ribosomes (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID: 27838525


There are 36 genes.  Reviewed (0 or Unreviewed (36

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Sah-0040
ENSSHAG00000009387.1
G3W635
2
LLPS-Sah-0451
ENSSHAG00000011388.1
G3WD17
3
LLPS-Sah-1268
ENSSHAG00000016178.1
G3WUF3
4
LLPS-Sah-1891
ENSSHAG00000005873.1
G3VUA2
5
LLPS-Sah-2915
ENSSHAG00000007140.1
G3VYI7
6
LLPS-Sah-3257
ENSSHAG00000004793.1
G3VQN0
7
LLPS-Sah-1240
ENSSHAG00000017514.1
G3WYZ7
AARS2
8
LLPS-Sah-0305
ENSSHAG00000006185.1
G3VVB2
DARS2
9
LLPS-Sah-2137
ENSSHAG00000006980.1
G3VXZ2
DHX30
10
LLPS-Sah-2832
ENSSHAG00000014995.1
G3WQF8
ERAL1
11
LLPS-Sah-0389
ENSSHAG00000017737.1
G3WZR2
FASTKD1
12
LLPS-Sah-1954
ENSSHAG00000016740.1
G3WWB3
FASTKD2
13
LLPS-Sah-2742
ENSSHAG00000002856.1
G3VJ83
FASTKD5
14
LLPS-Sah-3443
ENSSHAG00000018365.1
G3X1Y3
GRSF1
15
LLPS-Sah-3461
ENSSHAG00000005913.1
G3VUF2
HSD17B10
16
LLPS-Sah-3978
ENSSHAG00000006400.1
G3VW08
MCU
17
LLPS-Sah-1516
ENSSHAG00000014027.1
G3WM32
ME2
18
LLPS-Sah-3454
ENSSHAG00000016937.1
G3WX07
MRM2
19
LLPS-Sah-0052
ENSSHAG00000013782.1
G3WL87
MRPL43
20
LLPS-Sah-2435
ENSSHAG00000017273.1
G3WY60
MRPL47
21
LLPS-Sah-2134
ENSSHAG00000018455.1
G3X290
MRPS7
22
LLPS-Sah-1879
ENSSHAG00000018119.1
G3X121
MRPS9
23
LLPS-Sah-3373
ENSSHAG00000005026.1
G3VRF2
MTERF3
24
LLPS-Sah-1605
ENSSHAG00000001222.1
G3VDW7
MTPAP
25
LLPS-Sah-3220
ENSSHAG00000009158.1
G3W5A8
NLRX1
26
LLPS-Sah-0533
ENSSHAG00000001041.1
G3VDB2
PMPCB
27
LLPS-Sah-0125
ENSSHAG00000014040.1
G3WM47
PNPT1
28
LLPS-Sah-3439
ENSSHAG00000011376.1
G3WD01
PTCD1
29
LLPS-Sah-1534
ENSSHAG00000003833.1
G3VME9
PTCD2
30
LLPS-Sah-1292
ENSSHAG00000015536.1
G3WS98
RPUSD3
31
LLPS-Sah-2861
ENSSHAG00000008304.1
G3W2E2
RPUSD4
32
LLPS-Sah-1180
ENSSHAG00000000910.1
G3VCW1
SUPV3L1
33
LLPS-Sah-0000
ENSSHAG00000013259.1
G3WJF2
TFB1M
34
LLPS-Sah-2866
ENSSHAG00000008854.1
G3W497
TRMT10C
35
LLPS-Sah-1919
ENSSHAG00000013767.1
G3WL71
TWNK
36
LLPS-Sah-0972
ENSSHAG00000009522.1
G3W6K0
YME1L1