※ Mitochondrial RNA granule introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Mitochondrial RNA granules is a kind of these bodies of spherical shape that located in mitochondria with mitochondrial mRNAs and mitochondrial ribosomes components and it’s proved to be related to the posttranscriptional RNA processing and biogenesis of mitochondrial ribosomes (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID: 27838525

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No.	Status	DrLLPS ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		LLPS-Pat-2278	ENSPTRG00000018222.4	H2QT37	AARS2
2		LLPS-Pat-2917	ENSPTRG00000001698.7	H2R3I4	DARS2
3		LLPS-Pat-4429	ENSPTRG00000008258.3	H2QBD6	DDX28
4		LLPS-Pat-3443	ENSPTRG00000014877.5	A0A2I3TEM8	DHX30
5		LLPS-Pat-1806	ENSPTRG00000008938.3	H2QCJ4	ERAL1
6		LLPS-Pat-1390	ENSPTRG00000019874.6	H2QVM5	FASTK
7		LLPS-Pat-3681	ENSPTRG00000012616.6	H2QIY2	FASTKD1
8		LLPS-Pat-1912	ENSPTRG00000012848.5	A0A2J8N5S6	FASTKD2
9		LLPS-Pat-1081	ENSPTRG00000021929.7	H2QYN3	HSD17B10
10		LLPS-Pat-4534	ENSPTRG00000006263.7	H2Q865	KIAA0391
11		LLPS-Pat-1909	ENSPTRG00000019452.5	H2QV03	LOC104001074
12		LLPS-Pat-2327	ENSPTRG00000022948.5	A0A2I3SHP0	MCU
13		LLPS-Pat-3817	ENSPTRG00000010026.6	A0A2I3TUA7	ME2
14		LLPS-Pat-2761	ENSPTRG00000009049.6	H2R9M4	MRM1
15		LLPS-Pat-2609	ENSPTRG00000018857.6	H2QU32	MRM2
16		LLPS-Pat-2106	ENSPTRG00000008512.6	K7CMU7	MRM3
17		LLPS-Pat-0974	ENSPTRG00000012108.6	H2QI77	MRPL19
18		LLPS-Pat-3281	ENSPTRG00000002858.7	A0A2I3TT89	MRPL43
19		LLPS-Pat-1269	ENSPTRG00000015648.4	H2QNS6	MRPL47
20		LLPS-Pat-3970	ENSPTRG00000016967.6	A0A2I3S4V3	MRPS27
21		LLPS-Pat-1408	ENSPTRG00000005808.4	H2Q7G5	MRPS31
22		LLPS-Pat-2481	ENSPTRG00000009639.4	A0A2I3T0I2	MRPS7
23		LLPS-Pat-2317	ENSPTRG00000012310.3	H2QIH2	MRPS9
24		LLPS-Pat-3984	ENSPTRG00000020441.3	H2QWG6	MTERF3
25		LLPS-Pat-4250	ENSPTRG00000033794.3	K7B1T3	MTPAP
26		LLPS-Pat-1194	ENSPTRG00000004374.6	H2Q4Y0	NLRX1
27		LLPS-Pat-0391	ENSPTRG00000016088.5	H2QPI7	NOA1
28		LLPS-Pat-0689	ENSPTRG00000019551.6	G2HED1	PMPCB
29		LLPS-Pat-3715	ENSPTRG00000011934.6	A0A2I3T4K2	PNPT1
30		LLPS-Pat-3966	ENSPTRG00000010157.4	H2QES6	POLRMT
31		LLPS-Pat-0231	ENSPTRG00000016968.6	H2QR19	PTCD2
32		LLPS-Pat-2430	ENSPTRG00000051760.1	A0A2I3SNR3	RPUSD3
33		LLPS-Pat-4128	ENSPTRG00000004454.4	H2Q531	RPUSD4
34		LLPS-Pat-0223	ENSPTRG00000046048.1	A0A2I3SQ35	SUCLG2
35		LLPS-Pat-0286	ENSPTRG00000002568.6	H2Q204	SUPV3L1
36		LLPS-Pat-2499	ENSPTRG00000018730.7	H2QTY1	TFB1M
37		LLPS-Pat-4078	ENSPTRG00000015171.6	H2QN11	TRMT10C
38		LLPS-Pat-2102	ENSPTRG00000021423.5	H2QXY8	TRUB2
39		LLPS-Pat-4370	ENSPTRG00000029751.3	H2R7G8	TWNK
40		LLPS-Pat-3216	ENSPTRG00000002378.7	A0A2I3T6W9	YME1L1