Ornithorhynchus anatinus      Mitochondrial RNA granule


※ Mitochondrial RNA granule introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Mitochondrial RNA granules is a kind of these bodies of spherical shape that located in mitochondria with mitochondrial mRNAs and mitochondrial ribosomes components and it’s proved to be related to the posttranscriptional RNA processing and biogenesis of mitochondrial ribosomes (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID: 27838525


There are 37 genes.  Reviewed (0 or Unreviewed (37

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Ora-0074
ENSOANG00000009114.1
F7F1B4
2
LLPS-Ora-0140
ENSOANG00000014056.2
F7C9M2
3
LLPS-Ora-0701
ENSOANG00000011512.1
F6T458
4
LLPS-Ora-1495
ENSOANG00000002136.3
F6SVP3
5
LLPS-Ora-1945
ENSOANG00000001375.2
F7EM40
6
LLPS-Ora-2642
ENSOANG00000008691.3
F6PHD3
7
LLPS-Ora-2647
ENSOANG00000013696.3
F7G193
8
LLPS-Ora-2780
ENSOANG00000030392.1
K7EGY7
9
LLPS-Ora-2818
ENSOANG00000031308.1
F6TJI1
10
LLPS-Ora-3238
ENSOANG00000029761.1
K7EAF7
11
LLPS-Ora-3266
ENSOANG00000007327.2
F6WX85
12
LLPS-Ora-3332
ENSOANG00000012081.3
F7FQ24
13
LLPS-Ora-3352
ENSOANG00000014228.1
F6XBX1
14
LLPS-Ora-3368
ENSOANG00000003551.2
F7DQJ1
15
LLPS-Ora-3529
ENSOANG00000007326.3
F6W3S8
16
LLPS-Ora-0091
ENSOANG00000000921.3
F6QG19
DARS2
17
LLPS-Ora-1418
ENSOANG00000010513.1
F6ZHN5
DHX30
18
LLPS-Ora-1142
ENSOANG00000020472.2
F7FWQ1
FASTKD2
19
LLPS-Ora-1856
ENSOANG00000009214.1
F7G6V8
HSD17B10
20
LLPS-Ora-1282
ENSOANG00000001129.2
F6VSC1
MCU
21
LLPS-Ora-1892
ENSOANG00000008119.3
F7F489
ME2
22
LLPS-Ora-1494
ENSOANG00000009926.1
F6SS11
MRM3
23
LLPS-Ora-0711
ENSOANG00000009855.3
F7AJR3
MRPL19
24
LLPS-Ora-1594
ENSOANG00000004072.2
F6T329
MRPS27
25
LLPS-Ora-1481
ENSOANG00000015515.2
F6X1V1
MRPS31
26
LLPS-Ora-2192
ENSOANG00000008324.2
F6QGA5
MRPS7
27
LLPS-Ora-0191
ENSOANG00000012373.3
F7F842
MRPS9
28
LLPS-Ora-1796
ENSOANG00000001415.3
F7D2S2
MTERF3
29
LLPS-Ora-3125
ENSOANG00000006046.3
F6QKH8
MTPAP
30
LLPS-Ora-3176
ENSOANG00000012215.3
F7FPA8
NLRX1
31
LLPS-Ora-0400
ENSOANG00000000235.3
F6SM06
NOA1
32
LLPS-Ora-2044
ENSOANG00000011178.3
F7FRN1
PNPT1
33
LLPS-Ora-2330
ENSOANG00000014502.2
F6VGT1
PTCD2
34
LLPS-Ora-3140
ENSOANG00000007247.2
F6QNS2
RPUSD4
35
LLPS-Ora-0116
ENSOANG00000008886.2
F7EMA7
SUPV3L1
36
LLPS-Ora-2257
ENSOANG00000007508.2
F6PPN5
TRMT10C
37
LLPS-Ora-0545
ENSOANG00000006037.3
F6QLC7
YME1L1