Neurospora crassa      Mitochondrial RNA granule


※ Mitochondrial RNA granule introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Mitochondrial RNA granules is a kind of these bodies of spherical shape that located in mitochondria with mitochondrial mRNAs and mitochondrial ribosomes components and it’s proved to be related to the posttranscriptional RNA processing and biogenesis of mitochondrial ribosomes (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID: 27838525


There are 9 genes.  Reviewed (0 or Unreviewed (9

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Nec-0301
NCU06308
P38671
cyt-5
2
LLPS-Nec-1417
NCU03359
Q1K519
iap-1
3
LLPS-Nec-1295
NCU03827
Q7S7R6
mrp-9
4
LLPS-Nec-0694
NCU05287
Q7S910
mrpl-4
5
LLPS-Nec-0862
NCU01404
Q7S731
NCU01404
6
LLPS-Nec-0368
NCU02585
Q7SHN3
NCU02585
7
LLPS-Nec-0926
NCU06371
Q7S9T5
NCU06371
8
LLPS-Nec-0759
NCU07549
Q7S300
NCU07549
9
LLPS-Nec-1532
NCU11196
A7UVX8
NCU11196