Microbotryum violaceum      Mitochondrial RNA granule


※ Mitochondrial RNA granule introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Mitochondrial RNA granules is a kind of these bodies of spherical shape that located in mitochondria with mitochondrial mRNAs and mitochondrial ribosomes components and it’s proved to be related to the posttranscriptional RNA processing and biogenesis of mitochondrial ribosomes (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID: 27838525


There are 8 genes.  Reviewed (0 or Unreviewed (8

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Miv-1553
MVLG_01168
U5H1B0
MVLG_01168
2
LLPS-Miv-1395
MVLG_01516
U5H2C7
MVLG_01516
3
LLPS-Miv-1232
MVLG_01724
U5H2Z6
MVLG_01724
4
LLPS-Miv-0930
MVLG_02624
U5H5Q8
MVLG_02624
5
LLPS-Miv-0828
MVLG_02793
U5H689
MVLG_02793
6
LLPS-Miv-0957
MVLG_02962
U5H6R4
MVLG_02962
7
LLPS-Miv-0527
MVLG_03728
U5H933
MVLG_03728
8
LLPS-Miv-0868
MVLG_04644
U5HBV1
MVLG_04644