Mandrillus leucophaeus      Mitochondrial RNA granule


※ Mitochondrial RNA granule introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Mitochondrial RNA granules is a kind of these bodies of spherical shape that located in mitochondria with mitochondrial mRNAs and mitochondrial ribosomes components and it’s proved to be related to the posttranscriptional RNA processing and biogenesis of mitochondrial ribosomes (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID: 27838525


There are 39 genes.  Reviewed (0 or Unreviewed (39

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Mal-3444
ENSMLEG00000037448.1
A0A2K5ZFB5
2
LLPS-Mal-4271
ENSMLEG00000036668.1
A0A2K5ZB30
3
LLPS-Mal-4324
ENSMLEG00000031179.1
A0A2K5YEQ8
4
LLPS-Mal-4666
ENSMLEG00000035617.1
A0A2K5Z4Y3
AARS2
5
LLPS-Mal-4242
ENSMLEG00000044248.1
A0A2K6AK65
DARS2
6
LLPS-Mal-3071
ENSMLEG00000023203.1
A0A2K5XPN4
DHX30
7
LLPS-Mal-1366
ENSMLEG00000040246.1
A0A2K5ZW74
ERAL1
8
LLPS-Mal-3109
ENSMLEG00000029888.1
A0A2K5Y791
FASTK
9
LLPS-Mal-3986
ENSMLEG00000023795.1
A0A2K5XPZ3
FASTKD1
10
LLPS-Mal-3947
ENSMLEG00000030777.1
A0A2K5YCC6
FASTKD2
11
LLPS-Mal-4620
ENSMLEG00000007180.1
A0A2K5XEV7
GRSF1
12
LLPS-Mal-1993
ENSMLEG00000037754.1
A0A2K5ZGZ9
HSD17B10
13
LLPS-Mal-2056
ENSMLEG00000042381.1
A0A2K6A913
MCU
14
LLPS-Mal-3561
ENSMLEG00000041492.1
A0A2K6A4I6
ME2
15
LLPS-Mal-3404
ENSMLEG00000031933.1
A0A2K5YJ14
MRM1
16
LLPS-Mal-2541
ENSMLEG00000037490.1
A0A2K5ZFK5
MRM2
17
LLPS-Mal-4707
ENSMLEG00000034316.1
A0A2K5YXB0
MRM3
18
LLPS-Mal-1452
ENSMLEG00000032283.1
A0A2K5YKV1
MRPL19
19
LLPS-Mal-1334
ENSMLEG00000031351.1
A0A2K5YFY2
MRPL43
20
LLPS-Mal-2756
ENSMLEG00000028172.1
A0A2K5XXM8
MRPS27
21
LLPS-Mal-1372
ENSMLEG00000031037.1
A0A2K5YDW4
MRPS31
22
LLPS-Mal-2229
ENSMLEG00000032202.1
A0A2K5YKB0
MRPS7
23
LLPS-Mal-2404
ENSMLEG00000042789.1
A0A2K6ABD3
MRPS9
24
LLPS-Mal-3224
ENSMLEG00000029214.1
A0A2K5Y3C8
MTERF3
25
LLPS-Mal-0735
ENSMLEG00000043590.1
A0A2K6AGA7
MTPAP
26
LLPS-Mal-2822
ENSMLEG00000031404.1
A0A2K5YG22
NLRX1
27
LLPS-Mal-1114
ENSMLEG00000025732.1
A0A2K5XRV5
NOA1
28
LLPS-Mal-1212
ENSMLEG00000005693.1
A0A2K5XDS6
PMPCB
29
LLPS-Mal-3073
ENSMLEG00000038706.1
A0A2K5ZMM2
PNPT1
30
LLPS-Mal-1897
ENSMLEG00000037404.1
A0A2K5ZF09
POLRMT
31
LLPS-Mal-3925
ENSMLEG00000031093.1
A0A2K5YE38
PTCD2
32
LLPS-Mal-2394
ENSMLEG00000033940.1
A0A2K5YVA8
RPUSD3
33
LLPS-Mal-1251
ENSMLEG00000042461.1
A0A2K6A9L3
RPUSD4
34
LLPS-Mal-3938
ENSMLEG00000029579.1
A0A2K5Y5L6
SUCLG2
35
LLPS-Mal-3818
ENSMLEG00000028551.1
A0A2K5XZE1
SUPV3L1
36
LLPS-Mal-3446
ENSMLEG00000000044.1
A0A2K5X9L8
TFB1M
37
LLPS-Mal-3600
ENSMLEG00000037270.1
A0A2K5ZE63
TRUB2
38
LLPS-Mal-3445
ENSMLEG00000028857.1
A0A2K5Y198
TWNK
39
LLPS-Mal-1574
ENSMLEG00000036544.1
A0A2K5ZAT0
YME1L1