Loxodonta africana      Mitochondrial RNA granule


※ Mitochondrial RNA granule introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Mitochondrial RNA granules is a kind of these bodies of spherical shape that located in mitochondria with mitochondrial mRNAs and mitochondrial ribosomes components and it’s proved to be related to the posttranscriptional RNA processing and biogenesis of mitochondrial ribosomes (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID: 27838525


There are 40 genes.  Reviewed (0 or Unreviewed (40

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Loa-0021
ENSLAFG00000002588.3
G3SQS2
2
LLPS-Loa-4446
ENSLAFG00000009871.3
G3UEW8
3
LLPS-Loa-3214
ENSLAFG00000014270.3
G3TCX9
AARS2
4
LLPS-Loa-0886
ENSLAFG00000008719.3
G3T2D7
DARS2
5
LLPS-Loa-2376
ENSLAFG00000031239.1
G3U373
DDX28
6
LLPS-Loa-3955
ENSLAFG00000028880.1
G3TVG0
DHX30
7
LLPS-Loa-2061
ENSLAFG00000005438.2
G3SW84
ERAL1
8
LLPS-Loa-4473
ENSLAFG00000008796.2
G3U894
FASTK
9
LLPS-Loa-3686
ENSLAFG00000016410.4
G3TGY3
FASTKD1
10
LLPS-Loa-1653
ENSLAFG00000005198.2
G3SVR4
FASTKD2
11
LLPS-Loa-4400
ENSLAFG00000017032.4
G3TI30
GRSF1
12
LLPS-Loa-3507
ENSLAFG00000002368.2
G3U7Z8
HSD17B10
13
LLPS-Loa-3948
ENSLAFG00000004770.3
G3SUX0
MCU
14
LLPS-Loa-4476
ENSLAFG00000001536.3
G3SNR2
ME2
15
LLPS-Loa-1267
ENSLAFG00000012584.4
G3T9P0
MRM1
16
LLPS-Loa-1891
ENSLAFG00000008777.3
G3T2H4
MRM2
17
LLPS-Loa-3978
ENSLAFG00000016652.2
G3THE4
MRM3
18
LLPS-Loa-2834
ENSLAFG00000000146.4
G3SL61
MRPL19
19
LLPS-Loa-3959
ENSLAFG00000028961.1
G3UJH1
MRPL43
20
LLPS-Loa-0566
ENSLAFG00000018470.3
G3TKV9
MRPL47
21
LLPS-Loa-3951
ENSLAFG00000004110.2
G3STN2
MRPS27
22
LLPS-Loa-1175
ENSLAFG00000014360.3
G3TD34
MRPS31
23
LLPS-Loa-2230
ENSLAFG00000002873.2
G3SRB0
MRPS7
24
LLPS-Loa-0450
ENSLAFG00000008097.2
G3T166
MRPS9
25
LLPS-Loa-4046
ENSLAFG00000002544.2
G3SQP0
MTERF3
26
LLPS-Loa-2075
ENSLAFG00000013452.2
G3TBC5
MTPAP
27
LLPS-Loa-3247
ENSLAFG00000011977.3
G3U114
NLRX1
28
LLPS-Loa-3608
ENSLAFG00000003197.2
G3SRW5
NOA1
29
LLPS-Loa-3493
ENSLAFG00000021462.2
G3TNR0
PNPT1
30
LLPS-Loa-0374
ENSLAFG00000001860.4
G3SPD8
POLRMT
31
LLPS-Loa-1248
ENSLAFG00000004115.2
G3STN4
PTCD2
32
LLPS-Loa-4394
ENSLAFG00000017501.2
G3TJ03
RPUSD3
33
LLPS-Loa-0637
ENSLAFG00000005211.2
G3SVS0
RPUSD4
34
LLPS-Loa-3665
ENSLAFG00000015283.3
G3TEU9
SUCLG2
35
LLPS-Loa-1866
ENSLAFG00000000889.3
G3SMJ5
SUPV3L1
36
LLPS-Loa-1154
ENSLAFG00000014035.2
G3TCG6
TFB1M
37
LLPS-Loa-1606
ENSLAFG00000009677.2
G3TXV7
TRMT10C
38
LLPS-Loa-3026
ENSLAFG00000002174.3
G3SPZ1
TRUB2
39
LLPS-Loa-2806
ENSLAFG00000015859.3
G5E713
TWNK
40
LLPS-Loa-1345
ENSLAFG00000021743.2
G3TMJ0
YME1L1