Lepisosteus oculatus      Mitochondrial RNA granule


※ Mitochondrial RNA granule introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Mitochondrial RNA granules is a kind of these bodies of spherical shape that located in mitochondria with mitochondrial mRNAs and mitochondrial ribosomes components and it’s proved to be related to the posttranscriptional RNA processing and biogenesis of mitochondrial ribosomes (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID: 27838525


There are 39 genes.  Reviewed (0 or Unreviewed (39

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Leo-0038
ENSLOCG00000011122.1
W5MZ55
2
LLPS-Leo-0118
ENSLOCG00000005222.1
W5MD34
3
LLPS-Leo-0324
ENSLOCG00000008593.1
W5MPZ3
4
LLPS-Leo-0345
ENSLOCG00000015984.1
W5NGC2
5
LLPS-Leo-0369
ENSLOCG00000001431.1
W5LZS2
6
LLPS-Leo-0518
ENSLOCG00000010283.1
W5MW60
7
LLPS-Leo-0632
ENSLOCG00000009206.1
W5MS75
8
LLPS-Leo-0958
ENSLOCG00000012629.1
W5N4I8
9
LLPS-Leo-1191
ENSLOCG00000003928.1
W5M8I7
10
LLPS-Leo-1242
ENSLOCG00000004945.1
W5MC38
11
LLPS-Leo-1499
ENSLOCG00000012623.1
W5N4I1
12
LLPS-Leo-1746
ENSLOCG00000008722.1
W5MQG1
13
LLPS-Leo-1960
ENSLOCG00000000969.1
W5LY97
14
LLPS-Leo-2028
ENSLOCG00000017604.1
W5NM50
15
LLPS-Leo-2105
ENSLOCG00000008798.1
W5MQP9
16
LLPS-Leo-2226
ENSLOCG00000010389.1
W5MWH8
17
LLPS-Leo-2683
ENSLOCG00000017802.1
W5NMP7
18
LLPS-Leo-2756
ENSLOCG00000003302.1
W5M6A3
19
LLPS-Leo-2762
ENSLOCG00000013326.1
W5N715
20
LLPS-Leo-2959
ENSLOCG00000009172.1
W5MS28
21
LLPS-Leo-3067
ENSLOCG00000004833.1
W5MBP4
22
LLPS-Leo-3076
ENSLOCG00000011439.1
W5N0A3
23
LLPS-Leo-3091
ENSLOCG00000012857.1
W5N5C8
24
LLPS-Leo-3241
ENSLOCG00000001289.1
W5LZA3
25
LLPS-Leo-3338
ENSLOCG00000009159.1
W5MS15
26
LLPS-Leo-3416
ENSLOCG00000016850.1
W5NJM2
27
LLPS-Leo-3485
ENSLOCG00000011134.1
W5MZ67
28
LLPS-Leo-3604
ENSLOCG00000000885.1
W5LXX7
29
LLPS-Leo-3665
ENSLOCG00000008210.1
W5MNL0
30
LLPS-Leo-3786
ENSLOCG00000001287.1
W5LZC2
31
LLPS-Leo-3805
ENSLOCG00000007357.1
W5MKK3
32
LLPS-Leo-3816
ENSLOCG00000010214.1
W5MVU7
33
LLPS-Leo-3819
ENSLOCG00000008010.1
W5MMX3
34
LLPS-Leo-3948
ENSLOCG00000006115.1
W5MG82
35
LLPS-Leo-1799
ENSLOCG00000015678.1
W5NF89
AARS
36
LLPS-Leo-3427
ENSLOCG00000011589.1
W5N0T4
GRSF1
37
LLPS-Leo-2748
ENSLOCG00000015375.1
W5NE62
PNPT1
38
LLPS-Leo-1344
ENSLOCG00000010157.1
W5MVN3
SUCLG2
39
LLPS-Leo-3512
ENSLOCG00000000383.1
W5ML87
YME1L1