Canis familiaris      Mitochondrial RNA granule


※ Mitochondrial RNA granule introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Mitochondrial RNA granules is a kind of these bodies of spherical shape that located in mitochondria with mitochondrial mRNAs and mitochondrial ribosomes components and it’s proved to be related to the posttranscriptional RNA processing and biogenesis of mitochondrial ribosomes (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID: 27838525


There are 42 genes.  Reviewed (0 or Unreviewed (42

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Caf-3115
ENSCAFG00000001989.3
F1PA93
AARS2
2
LLPS-Caf-4241
ENSCAFG00000015055.4
J9NXC1
ATP5J2
3
LLPS-Caf-1871
ENSCAFG00000014522.3
F1PD07
DARS2
4
LLPS-Caf-1023
ENSCAFG00000020327.3
E2RKU0
DDX28
5
LLPS-Caf-4281
ENSCAFG00000013038.5
E2RL62
DHX30
6
LLPS-Caf-1261
ENSCAFG00000018813.3
E2QYF7
ERAL1
7
LLPS-Caf-3497
ENSCAFG00000004739.3
F1PFD7
FASTK
8
LLPS-Caf-3112
ENSCAFG00000012344.3
F1PUH2
FASTKD1
9
LLPS-Caf-1374
ENSCAFG00000013457.3
F1P7T1
FASTKD2
10
LLPS-Caf-2884
ENSCAFG00000024131.2
E2RHP5
FASTKD5
11
LLPS-Caf-1110
ENSCAFG00000002922.3
F1Q0B7
GRSF1
12
LLPS-Caf-4353
ENSCAFG00000016277.3
E2R9F5
HSD17B10
13
LLPS-Caf-0424
ENSCAFG00000013391.2
E2RMR1
KIAA0391
14
LLPS-Caf-1860
ENSCAFG00000014518.4
E2RAW0
MCU
15
LLPS-Caf-1979
ENSCAFG00000000168.3
E2R4S5
ME2
16
LLPS-Caf-4166
ENSCAFG00000017849.3
E2RN23
MRM1
17
LLPS-Caf-2501
ENSCAFG00000016434.3
E2R8N4
MRM2
18
LLPS-Caf-3352
ENSCAFG00000019117.3
E2QXE5
MRM3
19
LLPS-Caf-3951
ENSCAFG00000008175.3
E2R077
MRPL19
20
LLPS-Caf-1397
ENSCAFG00000009742.3
E2RN98
MRPL43
21
LLPS-Caf-3135
ENSCAFG00000011380.3
E2QXX0
MRPL47
22
LLPS-Caf-3266
ENSCAFG00000007967.3
E2R5P9
MRPS27
23
LLPS-Caf-2637
ENSCAFG00000005961.4
J9P5D6
MRPS31
24
LLPS-Caf-4339
ENSCAFG00000004752.2
E2RFN7
MRPS7
25
LLPS-Caf-4440
ENSCAFG00000002122.3
E2RKY3
MRPS9
26
LLPS-Caf-2892
ENSCAFG00000009460.3
E2RL82
MTERF3
27
LLPS-Caf-0863
ENSCAFG00000003984.3
E2RCU9
MTPAP
28
LLPS-Caf-2220
ENSCAFG00000012187.3
E2RA47
NLRX1
29
LLPS-Caf-4559
ENSCAFG00000002256.4
E2REA3
NOA1
30
LLPS-Caf-2133
ENSCAFG00000004166.3
F1PUK2
PMPCB
31
LLPS-Caf-2692
ENSCAFG00000002891.3
E2QWK2
PNPT1
32
LLPS-Caf-1192
ENSCAFG00000019711.4
J9P8Y8
POLRMT
33
LLPS-Caf-3998
ENSCAFG00000007982.3
F1Q1A5
PTCD2
34
LLPS-Caf-2552
ENSCAFG00000029733.1
J9NWF9
RPUSD3
35
LLPS-Caf-2808
ENSCAFG00000010488.3
F6XEH2
RPUSD4
36
LLPS-Caf-0774
ENSCAFG00000006612.4
F1PTK1
SUCLG2
37
LLPS-Caf-3603
ENSCAFG00000013839.3
F1PNI9
SUPV3L1
38
LLPS-Caf-4429
ENSCAFG00000000581.3
E2RQC3
TFB1M
39
LLPS-Caf-2771
ENSCAFG00000031607.1
J9P019
TRMT10C
40
LLPS-Caf-0181
ENSCAFG00000020068.4
J9P6Q3
TRUB2
41
LLPS-Caf-1915
ENSCAFG00000009753.3
E2RN86
TWNK
42
LLPS-Caf-0152
ENSCAFG00000004397.4
F1PRV6
YME1L1