Caenorhabditis elegans      Mitochondrial RNA granule


※ Mitochondrial RNA granule introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Mitochondrial RNA granules is a kind of these bodies of spherical shape that located in mitochondria with mitochondrial mRNAs and mitochondrial ribosomes components and it’s proved to be related to the posttranscriptional RNA processing and biogenesis of mitochondrial ribosomes (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID: 27838525


There are 22 genes.  Reviewed (0 or Unreviewed (22

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Cae-1107
WBGene00000181
Q19102
ard-1
2
LLPS-Cae-1977
WBGene00015266
Q965N3
BE0003N10.1
3
LLPS-Cae-1734
WBGene00007444
Q17828
C08F8.2
4
LLPS-Cae-1482
WBGene00008236
Q18746
C50F4.12
5
LLPS-Cae-1337
WBGene00021544
Q9N3X3
CELE_Y43B11AR.3
6
LLPS-Cae-0913
WBGene00012864
Q9XWY8
CELE_Y45F3A.9
7
LLPS-Cae-1146
WBGene00013001
O18196
CELE_Y48E1B.2
8
LLPS-Cae-0805
WBGene00001095
P90831
dars-2
9
LLPS-Cae-1762
WBGene00008456
Q09523
E02H1.2
10
LLPS-Cae-1505
WBGene00009735
O62251
F45G2.9
11
LLPS-Cae-2033
WBGene00019296
Q21121
mcu-1
12
LLPS-Cae-1698
WBGene00022470
Q95Y83
mrpl-19
13
LLPS-Cae-0494
WBGene00007712
O02220
mrpl-34
14
LLPS-Cae-0945
WBGene00015092
Q2L6V2
mrpl-47
15
LLPS-Cae-0918
WBGene00007859
Q09261
mrps-31
16
LLPS-Cae-1653
WBGene00013324
Q95Q11
mrps-7
17
LLPS-Cae-1042
WBGene00017319
P34388
mrps-9
18
LLPS-Cae-1342
WBGene00013680
A5PEY3
rpom-1
19
LLPS-Cae-1164
WBGene00016844
P53589
sucg-1
20
LLPS-Cae-0813
WBGene00020189
P91424
tfbm-1
21
LLPS-Cae-2072
WBGene00018514
Q5WRT0
twnk-1
22
LLPS-Cae-0464
WBGene00010842
P54813
ymel-1