Aspergillus oryzae      Mitochondrial RNA granule


※ Mitochondrial RNA granule introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Mitochondrial RNA granules is a kind of these bodies of spherical shape that located in mitochondria with mitochondrial mRNAs and mitochondrial ribosomes components and it’s proved to be related to the posttranscriptional RNA processing and biogenesis of mitochondrial ribosomes (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID: 27838525


There are 9 genes.  Reviewed (0 or Unreviewed (9

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Aso-0172
AO090001000745
Q2UMI2
AO090001000745
2
LLPS-Aso-0925
AO090003001068
Q2UJU6
AO090003001068
3
LLPS-Aso-0372
AO090009000229
Q2UUP9
AO090009000229
4
LLPS-Aso-1517
AO090010000459
Q2TWR1
AO090010000459
5
LLPS-Aso-0269
AO090012000268
Q2UD92
AO090012000268
6
LLPS-Aso-0784
AO090023000726
Q2UGS8
AO090023000726
7
LLPS-Aso-1396
AO090026000538
Q2UEP5
AO090026000538
8
LLPS-Aso-1501
AO090120000498
Q2U5V4
AO090120000498
9
LLPS-Aso-1453
AO090701000090
Q2U9C0
AO090701000090