Aspergillus clavatus      Mitochondrial RNA granule


※ Mitochondrial RNA granule introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Mitochondrial RNA granules is a kind of these bodies of spherical shape that located in mitochondria with mitochondrial mRNAs and mitochondrial ribosomes components and it’s proved to be related to the posttranscriptional RNA processing and biogenesis of mitochondrial ribosomes (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID: 27838525


There are 9 genes.  Reviewed (0 or Unreviewed (9

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Asc-1576
ACLA_013720
A1CB17
ACLA_013720
2
LLPS-Asc-1384
ACLA_016470
A1CBT3
ACLA_016470
3
LLPS-Asc-1031
ACLA_047700
A1CHE6
ACLA_047700
4
LLPS-Asc-1010
ACLA_050610
A1CI84
ACLA_050610
5
LLPS-Asc-1667
ACLA_052430
A1CIR5
ACLA_052430
6
LLPS-Asc-0792
ACLA_068050
A1C5V7
ACLA_068050
7
LLPS-Asc-1357
ACLA_074560
A1C7P8
ACLA_074560
8
LLPS-Asc-1075
ACLA_078590
A1CLY1
ACLA_078590
9
LLPS-Asc-1628
ACLA_096200
A1CMA0
ACLA_096200