Ashbya gossypii      Mitochondrial RNA granule


※ Mitochondrial RNA granule introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Mitochondrial RNA granules is a kind of these bodies of spherical shape that located in mitochondria with mitochondrial mRNAs and mitochondrial ribosomes components and it’s proved to be related to the posttranscriptional RNA processing and biogenesis of mitochondrial ribosomes (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID: 27838525


There are 7 genes.  Reviewed (0 or Unreviewed (7

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Asg-0357
AGOS_ACR224C
Q75BP7
AGOS_ACR224C
2
LLPS-Asg-0480
AGOS_ADL269W
Q75B46
AGOS_ADL269W
3
LLPS-Asg-1512
AGOS_AFL117C
Q755E0
AGOS_AFL117C
4
LLPS-Asg-0062
AGOS_AGL240W
Q751E6
AGOS_AGL240W
5
LLPS-Asg-0073
AGOS_AGL274W
Q751I0
AGOS_AGL274W
6
LLPS-Asg-0051
AGOS_AGR206C
Q74ZW3
AGOS_AGR206C
7
LLPS-Asg-0223
AGOS_AER033W
Q757I0
MRPS9