Aotus nancymaae      Mitochondrial RNA granule


※ Mitochondrial RNA granule introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Mitochondrial RNA granules is a kind of these bodies of spherical shape that located in mitochondria with mitochondrial mRNAs and mitochondrial ribosomes components and it’s proved to be related to the posttranscriptional RNA processing and biogenesis of mitochondrial ribosomes (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID: 27838525


There are 39 genes.  Reviewed (0 or Unreviewed (39

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Aon-0247
ENSANAG00000033690.1
A0A2K5EFE2
2
LLPS-Aon-0623
ENSANAG00000028210.1
A0A2K5DIS0
3
LLPS-Aon-1376
ENSANAG00000037296.1
A0A2K5F2Z3
4
LLPS-Aon-1382
ENSANAG00000022216.1
A0A2K5CI65
5
LLPS-Aon-1527
ENSANAG00000035790.1
A0A2K5ETM2
6
LLPS-Aon-1605
ENSANAG00000029895.1
A0A2K5DTS2
7
LLPS-Aon-1750
ENSANAG00000021821.1
A0A2K5CFT4
8
LLPS-Aon-3191
ENSANAG00000019945.1
A0A2K5C564
9
LLPS-Aon-3790
ENSANAG00000036067.1
A0A2K5EVF3
10
LLPS-Aon-4231
ENSANAG00000019918.1
A0A2K5C581
AARS2
11
LLPS-Aon-3318
ENSANAG00000021693.1
A0A2K5CF09
DARS2
12
LLPS-Aon-1005
ENSANAG00000024810.1
A0A2K5CZP7
DHX30
13
LLPS-Aon-1166
ENSANAG00000028784.1
A0A2K5DMB9
FASTK
14
LLPS-Aon-4165
ENSANAG00000026119.1
A0A2K5D6C2
FASTKD1
15
LLPS-Aon-3963
ENSANAG00000034550.1
A0A2K5EKU3
FASTKD2
16
LLPS-Aon-4685
ENSANAG00000022114.1
A0A2K5CHS6
GRSF1
17
LLPS-Aon-1232
ENSANAG00000028474.1
A0A2K5DK85
HSD17B10
18
LLPS-Aon-0279
ENSANAG00000034094.1
A0A2K5EHW5
MCU
19
LLPS-Aon-0378
ENSANAG00000024499.1
A0A2K5CX87
ME2
20
LLPS-Aon-2826
ENSANAG00000025500.1
A0A2K5D2N3
MRM1
21
LLPS-Aon-0313
ENSANAG00000030056.1
A0A2K5DUK0
MRM2
22
LLPS-Aon-2202
ENSANAG00000014643.1
A0A2K5BZ10
MRM3
23
LLPS-Aon-4025
ENSANAG00000034938.1
A0A2K5END3
MRPL43
24
LLPS-Aon-3652
ENSANAG00000019419.1
A0A2K5C316
MRPS27
25
LLPS-Aon-1322
ENSANAG00000028614.1
A0A2K5DKZ8
MRPS31
26
LLPS-Aon-1042
ENSANAG00000031075.1
A0A2K5E0P3
MTERF3
27
LLPS-Aon-2707
ENSANAG00000036595.1
A0A2K5EYM0
NLRX1
28
LLPS-Aon-3027
ENSANAG00000026721.1
A0A2K5D9U8
NOA1
29
LLPS-Aon-0984
ENSANAG00000023304.1
A0A2K5CPW4
PMPCB
30
LLPS-Aon-3682
ENSANAG00000023709.1
A0A2K5CSC5
PNPT1
31
LLPS-Aon-0178
ENSANAG00000032916.1
A0A2K5EAR4
POLRMT
32
LLPS-Aon-4496
ENSANAG00000029353.1
A0A2K5DQQ8
PTCD2
33
LLPS-Aon-2592
ENSANAG00000024050.1
A0A2K5CU45
RPUSD4
34
LLPS-Aon-3163
ENSANAG00000033664.1
A0A2K5EFB3
SUCLG2
35
LLPS-Aon-0160
ENSANAG00000022155.1
A0A2K5CHY9
SUPV3L1
36
LLPS-Aon-3330
ENSANAG00000021469.1
A0A2K5CDQ5
TFB1M
37
LLPS-Aon-2668
ENSANAG00000036234.1
A0A2K5EW75
TRUB2
38
LLPS-Aon-2088
ENSANAG00000022264.1
A0A2K5CIE2
TWNK
39
LLPS-Aon-0136
ENSANAG00000030831.1
A0A2K5E0V2
YME1L1