Anolis carolinensis      Mitochondrial RNA granule


※ Mitochondrial RNA granule introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Mitochondrial RNA granules is a kind of these bodies of spherical shape that located in mitochondria with mitochondrial mRNAs and mitochondrial ribosomes components and it’s proved to be related to the posttranscriptional RNA processing and biogenesis of mitochondrial ribosomes (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID: 27838525


There are 41 genes.  Reviewed (0 or Unreviewed (41

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Anc-3690
ENSACAG00000010127.3
H9GG22
2
LLPS-Anc-1253
ENSACAG00000014588.2
G1KQ51
AARS2
3
LLPS-Anc-2086
ENSACAG00000015426.3
G1KR37
DARS2
4
LLPS-Anc-3624
ENSACAG00000009755.2
H9GFJ1
DDX28
5
LLPS-Anc-0494
ENSACAG00000017696.3
H9GPJ8
DHX30
6
LLPS-Anc-0935
ENSACAG00000005313.3
H9GA41
fastk
7
LLPS-Anc-1676
ENSACAG00000017101.3
H9GS28
fastkd1
8
LLPS-Anc-0471
ENSACAG00000009610.3
H9GFE7
FASTKD2
9
LLPS-Anc-4034
ENSACAG00000012921.3
G1KN05
GRSF1
10
LLPS-Anc-3551
ENSACAG00000009337.3
G1KIS0
HSD17B10
11
LLPS-Anc-0692
ENSACAG00000001929.2
G1KA25
kiaa0391
12
LLPS-Anc-0537
ENSACAG00000000515.3
H9G3S4
LOC103282303
13
LLPS-Anc-3179
ENSACAG00000000862.3
G1K8V1
MCU
14
LLPS-Anc-3782
ENSACAG00000010123.3
H9GG26
me2
15
LLPS-Anc-3087
ENSACAG00000002573.3
H9G6C9
MRM1
16
LLPS-Anc-3332
ENSACAG00000009089.2
H9GER0
MRM2
17
LLPS-Anc-3185
ENSACAG00000015977.3
H9GMT3
mrm3
18
LLPS-Anc-1127
ENSACAG00000013523.3
G1KNX5
MRPL19
19
LLPS-Anc-0066
ENSACAG00000003798.3
G1KC87
MRPL43
20
LLPS-Anc-1292
ENSACAG00000004517.3
G1KCV8
MRPL47
21
LLPS-Anc-1004
ENSACAG00000009787.3
G1KJD7
MRPS27
22
LLPS-Anc-0086
ENSACAG00000016639.3
G1KSV3
MRPS31
23
LLPS-Anc-1730
ENSACAG00000006441.3
G1KFD7
MRPS7
24
LLPS-Anc-0276
ENSACAG00000011232.3
H9GHG4
MRPS9
25
LLPS-Anc-1982
ENSACAG00000004143.3
G1KCK0
MTERF3
26
LLPS-Anc-1427
ENSACAG00000007513.3
G1KGP4
MTPAP
27
LLPS-Anc-3172
ENSACAG00000002300.3
H9G638
NLRX1
28
LLPS-Anc-3089
ENSACAG00000002327.3
H9G649
NOA1
29
LLPS-Anc-1329
ENSACAG00000006504.3
G1KFG6
PMPCB
30
LLPS-Anc-1585
ENSACAG00000003692.3
G1KCA1
PNPT1
31
LLPS-Anc-0791
ENSACAG00000012871.3
H9GJE9
ptcd1
32
LLPS-Anc-1163
ENSACAG00000009747.3
G1KJB5
PTCD2
33
LLPS-Anc-2867
ENSACAG00000009836.3
G1KJD6
RPUSD3
34
LLPS-Anc-1798
ENSACAG00000000189.2
H9G3D2
RPUSD4
35
LLPS-Anc-1400
ENSACAG00000015144.3
G1KQT2
SUCLG2
36
LLPS-Anc-2023
ENSACAG00000009685.3
H9GFJ2
SUPV3L1
37
LLPS-Anc-2852
ENSACAG00000005244.3
G1KDU6
TFB1M
38
LLPS-Anc-2497
ENSACAG00000011903.3
G1KXE4
TRMT10C
39
LLPS-Anc-2804
ENSACAG00000007331.3
H9GCK4
TRUB2
40
LLPS-Anc-2792
ENSACAG00000003783.3
G1KC80
TWNK
41
LLPS-Anc-2402
ENSACAG00000007861.3
G1KHA6
YME1L1