Mustela putorius furo      Microtubule


※ Microtubule introduction

    Microtubules (MTs) are tubulin heterodimers that are arranged in a parallel shape of hollow cylinders which play roles in regulating the mechanical structure and dynamics of cells. Much of the structure and dynamics of MTs is highly ordered (1). In fact, microtubules were enable to be used as platforms to understand the mechanisms underlying liquid–liquid phase separation, some RNA binding proteins on microtubules leads to the formation of mRNA-rich liquid-like compartments on microtubules (2).

Reference
1. Ilan, Y. (2019) Randomness in microtubule dynamics: an error that requires correction or an inherent plasticity required for normal cellular function? Cell Biol Int, PMID: 31042006
2. Maucuer, A., Desforges, B., Joshi, V., Boca, M., Kretov, D. A., Hamon, L., et al. (2018) Microtubules as platforms for probing liquid-liquid phase separation in cells - application to RNA-binding proteins. J Cell Sci, 131(11). PMID: 29728455


There are 3 genes.  Reviewed (0 or Unreviewed (3

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Mup-1160
ENSMPUG00000011723.1
M3YJX2
POC1A
2
LLPS-Mup-1897
ENSMPUG00000007581.1
M3Y868
POC1B
3
LLPS-Mup-2364
ENSMPUG00000016605.1
M3YYU1
TUBA4A