※ Microtubule introduction

    Microtubules (MTs) are tubulin heterodimers that are arranged in a parallel shape of hollow cylinders which play roles in regulating the mechanical structure and dynamics of cells. Much of the structure and dynamics of MTs is highly ordered (1). In fact, microtubules were enable to be used as platforms to understand the mechanisms underlying liquid–liquid phase separation, some RNA binding proteins on microtubules leads to the formation of mRNA-rich liquid-like compartments on microtubules (2).

Reference
1. Ilan, Y. (2019) Randomness in microtubule dynamics: an error that requires correction or an inherent plasticity required for normal cellular function? Cell Biol Int, PMID: 31042006
2. Maucuer, A., Desforges, B., Joshi, V., Boca, M., Kretov, D. A., Hamon, L., et al. (2018) Microtubules as platforms for probing liquid-liquid phase separation in cells - application to RNA-binding proteins. J Cell Sci, 131(11). PMID: 29728455

  Reviewed (0)  or Unreviewed (4) 

No.	Status	DrLLPS ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		LLPS-Aon-0458	ENSANAG00000026545.1	A0A2K5D8Z2	MAPT
2		LLPS-Aon-0980	ENSANAG00000030897.1	A0A2K5DZS5	POC1A
3		LLPS-Aon-4699	ENSANAG00000023816.1	A0A2K5CSW3	POC1B
4		LLPS-Aon-0890	ENSANAG00000028048.1	A0A2K5DHT5	TUBA4A