Yarrowia lipolytica      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 6 genes.  Reviewed (0 or Unreviewed (6

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Yal-0806
YALI0_E03982g
Q6C740
CFT1
2
LLPS-Yal-0295
YALI0_E02882g
Q6C784
FIP1
3
LLPS-Yal-0104
YALI0_F02827g
Q6C341
HTZ1
4
LLPS-Yal-1041
YALI0_A15686g
Q6CGV9
YALI0_A15686g
5
LLPS-Yal-1097
YALI0_C23232g
Q6CAZ0
YALI0_C23232g
6
LLPS-Yal-1364
YALI0_F03817g
Q6C2Z7
YSH1