Tursiops truncatus      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 6 genes.  Reviewed (0 or Unreviewed (6

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Tut-0115
ENSTTRG00000009184.1
A0A2U4BDE5
CTCF
2
LLPS-Tut-1565
ENSTTRG00000002809.1
A0A2U3V031
HINFP
3
LLPS-Tut-0057
ENSTTRG00000006061.1
A0A2U4BWI8
LOC101319171
4
LLPS-Tut-0853
ENSTTRG00000013336.1
A0A2U4B780
LOC101330110
5
LLPS-Tut-1014
ENSTTRG00000006956.1
A0A2U4BN90
LOC101332802
6
LLPS-Tut-1283
ENSTTRG00000006445.1
A0A2U4AHW0
LSM11