Tetraodon nigroviridis      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 15 genes.  Reviewed (0 or Unreviewed (15

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Ten-0104
ENSTNIG00000006091.1
H3CKQ6
2
LLPS-Ten-0177
ENSTNIG00000006265.1
H3CL89
3
LLPS-Ten-0248
ENSTNIG00000017066.1
H3DI54
4
LLPS-Ten-0537
ENSTNIG00000015629.1
H3DDW0
5
LLPS-Ten-0826
ENSTNIG00000009314.1
H3CV96
6
LLPS-Ten-0859
ENSTNIG00000012228.1
H3D3V6
7
LLPS-Ten-1183
ENSTNIG00000014027.1
H3D943
8
LLPS-Ten-1372
ENSTNIG00000009364.1
H3CVE8
9
LLPS-Ten-1537
ENSTNIG00000004104.1
H3CEP6
10
LLPS-Ten-1802
ENSTNIG00000003334.1
H3CCE8
11
LLPS-Ten-1974
ENSTNIG00000017855.1
H3DKG8
12
LLPS-Ten-2575
ENSTNIG00000011746.1
H3D2F9
13
LLPS-Ten-3219
ENSTNIG00000003695.1
H3CDH1
14
LLPS-Ten-3068
ENSTNIG00000017313.1
H3C2X6
CPSF3 (1 of many)
15
LLPS-Ten-0699
ENSTNIG00000019425.1
Q4RE31
GSTENG00035951001