Taeniopygia guttata      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 16 genes.  Reviewed (0 or Unreviewed (16

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Tag-0818
ENSTGUG00000017414.1
H1A477
2
LLPS-Tag-1698
ENSTGUG00000007679.1
H0ZBF1
3
LLPS-Tag-1739
ENSTGUG00000001600.1
H0YTN6
4
LLPS-Tag-2498
ENSTGUG00000001602.1
H0YTN7
5
LLPS-Tag-2606
ENSTGUG00000012385.1
H0ZQ59
6
LLPS-Tag-2883
ENSTGUG00000007834.1
H0ZBW6
7
LLPS-Tag-1563
ENSTGUG00000012571.1
H0ZQQ7
CPSF2
8
LLPS-Tag-2155
ENSTGUG00000013016.1
H0ZS16
CPSF3
9
LLPS-Tag-2128
ENSTGUG00000007552.1
H0ZB24
CPSF4
10
LLPS-Tag-1169
ENSTGUG00000005603.1
H0Z5D2
CTCF
11
LLPS-Tag-1030
ENSTGUG00000007907.1
H0ZC78
CTR9
12
LLPS-Tag-1899
ENSTGUG00000013660.1
H0ZTZ6
DDX20
13
LLPS-Tag-1472
ENSTGUG00000015225.1
H0ZY77
H2AFV
14
LLPS-Tag-1259
ENSTGUG00000000357.1
H0YQ14
HINFP
15
LLPS-Tag-3340
ENSTGUG00000000615.1
H0YQR8
LSM11
16
LLPS-Tag-0506
ENSTGUG00000012634.1
H0ZQW9
NPAT