Sporisorium reilianum      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 7 genes.  Reviewed (0 or Unreviewed (7

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Spr-1080
sr10150
E6ZKM6
sr10150
2
LLPS-Spr-1322
sr12533
E6ZWS0
sr12533
3
LLPS-Spr-1123
sr13886
E7A169
sr13886
4
LLPS-Spr-0440
sr15233
E6ZPK7
sr15233
5
LLPS-Spr-0020
sr15826
E6ZQ54
sr15826
6
LLPS-Spr-0940
sr16415
E6ZSK3
sr16415
7
LLPS-Spr-1339
sr16769
E6ZWA2
sr16769