Setaria italica      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 6 genes.  Reviewed (0 or Unreviewed (6

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Sei-0358
SETIT_037967mg
K4AGG0
101757439
2
LLPS-Sei-0762
SETIT_028720mg
K3ZQ41
101757641
3
LLPS-Sei-1566
SETIT_029047mg
K3ZR17
101764527
4
LLPS-Sei-1189
SETIT_034495mg
K4A6J0
101772119
5
LLPS-Sei-1803
SETIT_016168mg
K3YPH6
101783261
6
LLPS-Sei-1230
SETIT_009198mg
A0A368RRF4
SETIT_7G028600v2