Selaginella moellendorffii      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 7 genes.  Reviewed (0 or Unreviewed (7

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Sem-0605
SELMODRAFT_122533
D8SQE3
SELMODRAFT_122533
2
LLPS-Sem-0139
SELMODRAFT_149863
D8RTU4
SELMODRAFT_149863
3
LLPS-Sem-0528
SELMODRAFT_184138
D8SZQ2
SELMODRAFT_184138
4
LLPS-Sem-2008
SELMODRAFT_234972
D8SSB6
SELMODRAFT_234972
5
LLPS-Sem-0093
SELMODRAFT_441578
D8RKS9
SELMODRAFT_441578
6
LLPS-Sem-1374
SELMODRAFT_442688
D8RVC1
SELMODRAFT_442688
7
LLPS-Sem-0732
SELMODRAFT_412601
D8RM07
SHL1A-1