Schizosaccharomyces japonicus      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 6 genes.  Reviewed (0 or Unreviewed (6

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Scj-0914
SJAG_00139
B6JXJ7
SJAG_00139
2
LLPS-Scj-0849
SJAG_00961
B6JX34
SJAG_00961
3
LLPS-Scj-0988
SJAG_03047
B6K365
SJAG_03047
4
LLPS-Scj-0951
SJAG_03226
B6K3N6
SJAG_03226
5
LLPS-Scj-1304
SJAG_03233
B6K3P3
SJAG_03233
6
LLPS-Scj-1099
SJAG_04587
B6K781
SJAG_04587