Physcomitrella patens      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 9 genes.  Reviewed (0 or Unreviewed (9

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Php-2251
Pp3c2_10640
A0A2K1L114
PHYPA_002504
2
LLPS-Php-0901
Pp3c3_17140
A0A2K1KUW4
PHYPA_004552
3
LLPS-Php-0459
Pp3c4_14220
A0A2K1KNE6
PHYPA_006194
4
LLPS-Php-0774
Pp3c5_23920
A9RRH1
PHYPA_008086
5
LLPS-Php-1190
Pp3c7_2840
A0A2K1KA22
PHYPA_009822
6
LLPS-Php-0423
Pp3c9_11100
A0A2K1K2T2
PHYPA_012564
7
LLPS-Php-0080
Pp3c11_8810
A0A2K1JU02
PHYPA_014777
8
LLPS-Php-0580
Pp3c11_10290
A9SAY0
PHYPA_014850
9
LLPS-Php-2442
Pp3c21_11710
A0A2K1IRM3
PHYPA_026057