Phaeosphaeria nodorum      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 6 genes.  Reviewed (0 or Unreviewed (6

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Phn-0723
SNOG_04622
Q0UUE2
CFT1
2
LLPS-Phn-1041
SNOG_09221
Q0UG93
HTZ1
3
LLPS-Phn-0707
SNOG_01891
Q0V273
SNOG_01891
4
LLPS-Phn-0924
SNOG_02691
Q0UZX3
SNOG_02691
5
LLPS-Phn-0609
SNOG_04721
Q0UU43
SNOG_04721
6
LLPS-Phn-0564
SNOG_09115
Q0UGJ9
SNOG_09115