Papio anubis      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 17 genes.  Reviewed (0 or Unreviewed (17

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Paa-0980
ENSPANG00000019486.3
A0A096NTF9
BAHCC1
2
LLPS-Paa-2554
ENSPANG00000016264.2
A0A2I3LXZ1
CASP8AP2
3
LLPS-Paa-2242
ENSPANG00000015005.2
A0A096N7N7
CPSF1
4
LLPS-Paa-1082
ENSPANG00000017417.2
A0A096NJE2
CPSF2
5
LLPS-Paa-1204
ENSPANG00000016798.2
A0A096NIU8
CPSF3
6
LLPS-Paa-1671
ENSPANG00000023123.2
A0A096N5S3
CPSF4
7
LLPS-Paa-4658
ENSPANG00000015703.3
A0A096NZP9
CTCF
8
LLPS-Paa-2979
ENSPANG00000019132.2
A0A096MTM5
CTR9
9
LLPS-Paa-0952
ENSPANG00000017985.3
A0A096N683
DDX20
10
LLPS-Paa-0727
ENSPANG00000011213.2
A0A096NBS8
FIP1L1
11
LLPS-Paa-2996
ENSPANG00000011456.3
A0A096MRS4
GON4L
12
LLPS-Paa-2038
ENSPANG00000008062.2
A0A2I3MDP8
H2AFV
13
LLPS-Paa-2345
ENSPANG00000005040.2
A0A096N8F5
HINFP
14
LLPS-Paa-3367
ENSPANG00000023172.2
A0A096ND46
LSM10
15
LLPS-Paa-1973
ENSPANG00000026022.2
A0A096NCP6
NPAT
16
LLPS-Paa-3465
ENSPANG00000019930.2
A0A2I3MD06
SYMPK
17
LLPS-Paa-1329
ENSPANG00000024061.2
A0A2I3MCI3
TP53